SYSTEM AND METHOD FOR APPLYING THERAPY TO AN EYE USING ENERGY CONDUCTION

• US 20090275936A1
• Filed: 05/01/2008
• Published: 11/05/2009
• Est. Priority Date: 05/01/2008
• Status: Abandoned Application

• Current Assignee: Avedro, Inc. (Glaukos Corporation)
• Original Assignee: Avedro, Inc. (Glaukos Corporation)
• Inventors: Muller, David
• Application Number:
  US12/113,672
• Publication Number:
  US 20090275936A1
• Time in Patent Office: Days
• US Class Current: 606/33
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61F 9/00 Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand caps with means for protecting the eyes A42B1/018; visors for helmets A42B3/22; retractors A61B17/02; manipulators specially adapted for use in surgery A61B34/70; appliances to aid invalids to move about A61H3/00; exercisers for the eyes A61H5/00; eye baths A61H35/02; sunglasses or goggles having the same features as spectacles G02C
• CPC Class Codes: A61F 9/0079 using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
• CPC Class Codes: A61F 9/013 Instruments for compensation of ocular refraction A61F9/008 takes precedence; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea

Abstract

Thermokeratoplasty is applied to achieve a customized reshaping of a cornea, especially, for the treatment of astigmatism. Energy is applied to the cornea in a customized pattern using a specific configuration of two conductors. In one embodiment, an outer conductor and an outer conductor are separated by a gap. When a conducting element is applied to the corneal surface the area of the cornea at the periphery of the inner conductor is subject to an energy pattern with substantially the same shape and dimension as the gap between the inner and outer conductors. The inner and outer conductors may be positioned and shaped to form a gap having any desirable size and/or shape, including non-annular and asymmetrical shapes. The gap may be configured by altering the spatial relationships between the inner conductor and the outer conductor, by altering the size, shape, and/or position of the inner and/or outer conductors, or by forming one or more indentations or protrusions in or on the inner conductor and/or the outer conductor. Additionally or alternatively, energy is applied to the cornea in a customized pattern defined by a specific arrangement of one or more dielectric materials providing varying impedance.

Claims

1. An energy conducting system for applying therapy to an eye, the energy conducting system comprising:

an energy conducting element including a first conductor and a second conductor, the first conductor and the second conductor extending to an application end and being separated by a gap; and

a positioning system receiving the energy conducting element and positioning the application end relative to a feature of an eye, the gap between the first conductor and the second conductor providing a pattern by which energy is delivered to the eye, the pattern being at least one of non-annular and asymmetric with respect to the eye feature.

2. The energy conducting system of claim 1, wherein the gap has a varying thickness defined by more than one distance between the first conductor and the second conductor.

3. The energy conducting system of claim 1, wherein the gap has a substantially constant thickness defined by substantially one distance between the first conductor and the second conductor.

4. The energy conducting system of claim 1, wherein the gap is substantially non-annular.

5. The energy conducting system of claim 1, wherein the gap is asymmetric relative to at least one transverse axis.

6. The energy conducting system of claim 1, wherein the gap is defined at least by an indentation that extends into at least one of the first conductor and the second conductor.

7. The energy conducting system of claim 6, wherein the indentation is a notch.

8. The energy conducting system of claim 6, wherein the indentation is curved.

9. The energy conducting system of claim 1, wherein the gap is defined at least by a protrusion that extends from at least one of the first conductor and the second conductor.

10. The energy conducting system of claim 9, wherein the protrusion has an angled shape.

11. The energy conducting system of claim 9, wherein the protrusion is curved.

12. The energy conducting system of claim 1, wherein the pattern is segmented according to at least one of the first conductor and the second conductor being segmented into more than two sections.

13. The energy conducting system of claim 12, wherein at least one of the first conductor and the second conductor are segmented into more than two sections according to a layer of at least one dielectric material, the layer providing varying impedance.

14. The energy conducting system of claim 1, wherein the application end includes a layer of at least one dielectric material, the layer providing varying impedance.

15. The energy conducting system of claim 1, wherein the first conductor and the second conductor are substantially planar and parallel to each other.

16. The energy conducting system of claim 1, wherein the first conductor is an outer conductor having an interior surface defining a longitudinal interior passageway;

and the second conductor is an inner conductor positioned within the interior passageway of the outer conductor.

17. The energy conducting system of claim 16, wherein the inner conductor has an exterior surface separated from the outer conductor by a non-annular gap.

18. The energy conducting system of claim 16, wherein the inner conductor has an exterior surface separated from the interior surface of the outer conductor by the gap, the gap having a varying thickness defined by more than one distance between the exterior surface of the inner conductor and the interior surface of the outer conductor.

19. The energy conducting system of claim 1, wherein the application end includes an eye contact portion configured to apply the energy to an eye feature and providing a reshaping mold to reshape the eye feature as the eye feature responds to the application of the energy.

20. The energy conducting system of claim 1, wherein the positioning system comprises a vacuum fixation device creating a vacuum connection with an eye and to position the energy conducting element relative to the eye, whereby the energy conducting element directs the energy to the eye.

21. The energy conducting system of claim 1, wherein the application end is one of a plurality of removably attachable end pieces.

22. An energy conducting system for applying therapy to an eye, the energy conducting system comprising:

an outer conductor having an interior surface defining an interior passageway; and

an inner conductor positioned within the interior passageway, the inner conductor having an exterior surface separated from the interior surface of the outer conductor by a gap, the gap being at least one of non-annular and asymmetric,

wherein the outer conductor and inner conductor define an application end positionable at an eye, the outer conductor and inner conductor conducting energy to the eye via the application end according to a pattern defined at least by the gap.

23. The energy conducting system of claim 22, wherein the inner conductor has an inner-conductor center axis that is offset from an interior-passageway center axis of the interior passageway.

24. The energy conducting system of claim 23, wherein the interior passageway and the inner conductor are substantially cylindrical.

25. The energy conducting system of claim 23, wherein the interior passageway and the inner conductor have transverse profiles that are substantially elliptical.

26. The energy conducting system of claim 23, wherein the inner-conductor center axis is adjustably movable relative to the interior-passageway center axis.

27. The energy conducting system of claim 22, wherein the gap between the inner conductor and the outer conductor has a transverse profile that is substantially elliptical.

28. The energy conducting system of claim 22, wherein the gap has a varying thickness defined by more than one distance between the outer conductor and the inner conductor.

30. The energy conducting system of claim 22, wherein the gap is defined at least by an indentation that extends into at least one of the outer conductor and the inner conductor.

31. The energy conducting system of claim 30, wherein the indentation is a notch.

32. The energy conducting system of claim 30, wherein the indentation is curved.

33. The energy conducting system of claim 22, wherein the gap is defined at least by a protrusion that extends from at least one of the first conductor and the second conductor.

34. The energy conducting system of claim 33, wherein the protrusion has an angled shape.

35. The energy conducting system of claim 33, wherein the protrusion is curved.

36. The energy conducting system of claim 22, wherein at least one of the outer conductor and the inner conductor being segmented into more than two sections.

37. The energy conducting system of claim 36, wherein at least one of the outer conductor and the inner conductor are segmented into more than two sections according to a layer of at least one dielectric material, the layer providing varying impedance.

38. The energy conducting system of claim 22, wherein the application end includes a layer of at least one dielectric material, the layer providing varying impedance.

39. The energy conducting system of claim 22, wherein the application end includes an eye contact portion configured to apply the energy to an eye feature and providing a reshaping mold to reshape the eye feature as the eye feature responds to the application of the energy.

40. The energy conducting system of claim 22, further comprising a positioning system receiving the outer conductor and the inner conductor and positioning the application end relative to a feature of an eye.

41. The energy conducting system of claim 40, wherein the positioning system comprises a vacuum fixation device creating a vacuum connection with an eye and to position the energy conducting element relative to the eye, whereby the energy conducting element directs the energy to the eye.

42. The energy conducting system of claim 22, wherein the application end is one of a plurality of removably attachable end pieces.

29. The energy conducting system of 22, wherein the gap has a substantially constant thickness defined by substantially one distance between the first conductor and the second conductor.

43. An energy conducting system for applying therapy to an eye, the energy conducting system comprising:

an energy conducting element including a first conductor and a second conductor, the first conductor and the second conductor extending to an application end and being separated by a gap; and

one or more materials providing varying impedance, the one or more materials being applied, at the application end, to at least one of the first conductor and the second conductor, the first conductor and the second conductor conducting energy to the eye via the application end at least according to a pattern defined by the varying impedance.

44. The energy conducting system of claim 43, wherein the one or more materials includes a material applied in layers of varying thickness to provide varying impedance.

45. The energy conducting system of claim 43, wherein the one or more materials includes materials that provide varying impedance for a given applied thickness.

46. The energy conducting system of claim 43, wherein the pattern for conducting energy is asymmetric.

47. The energy conducting system of claim 43, wherein the pattern for conducting energy is non-annular.

48. The energy conducting system of claim 43, wherein the pattern for conducting energy is substantially elliptical.

49. The energy conducting system of claim 43, wherein the varying impedance includes at least one area of high impedance preventing conduction of energy therefrom and at least one area of low impedance allowing conduction of energy therefrom, the areas of high impedance and the areas of low impedance defining the pattern for conducting energy via the application end.

50. The energy conducting system of claim 49, wherein the at least one area of low impedance includes at least one protrusion extending into the gap.

51. The energy conducting system of claim 49, wherein the at least one area of low impedance includes at least one indentation extending from the gap.

52. The energy conducting system of claim 43, wherein the gap is non-annular.

53. The energy conducting system of claim 43, wherein the gap is asymmetric.

54. The energy conducting system of claim 43, wherein the gap includes a protrusion.

55. The energy conducting system of claim 43, wherein the gap includes an indentation.

56. The energy conducting system of claim 43, wherein the first conductor is an outer conductor having an interior surface defining a longitudinal interior passageway;

and the second conductor is an inner conductor positioned within the interior passageway of the outer conductor.

57. The energy conducting system of claim 56, wherein the one or more materials is applied to the inner conductor, the application of the one or more materials including a circular area of high impedance and an annular area of low impedance surrounding the circular area of high impedance.

58. The energy conducting system of claim 43, wherein the application end includes an eye contact portion configured to apply the energy to an eye feature and providing a reshaping mold to reshape the eye feature as the eye feature responds to the application of the energy.

59. The energy conducting system of claim 43, further comprising a positioning system receiving the energy conducting element and positioning the application end relative to a feature of an eye.

60. The energy conducting system of claim 59, wherein the positioning system comprises a vacuum fixation device creating a vacuum connection with an eye and to position the energy conducting element relative to the eye, whereby the energy conducting element directs the energy to the eye.

61. The energy conducting system of claim 43, wherein the application end is one of a plurality of removably attachable end pieces.

62. A method for applying therapy to an eye with a conducting system comprising an energy conducting element including a first conductor and a second conductor, the first conductor and the second conductor extending to an application end and being separated by a gap, and a positioning system receiving the energy conducting element, the method comprising the steps of:

determining a gap separating the first conductor and the second conductor;

positioning, with the positioning system, the application end of the energy conducting element at an eye; and

reshaping an eye feature by applying energy to the eye via the conducting element according to a pattern, the pattern being defined at least by the gap and the position of the application end relative to the eye and being at least one of non-annular and asymmetric with respect to the eye feature.

63. The method of claim 62, wherein the step of determining a gap comprises providing a gap with a varying thickness defined by more than one distance between the first conductor and the second conductor.

64. The method of claim 62, wherein the step of determining a gap comprises providing a gap with a substantially constant thickness defined by substantially one distance between the first conductor and the second conductor.

65. The method of claim 62, wherein the step of determining a gap comprises providing a gap that is substantially non-annular.

66. The method of claim 62, wherein the step of determining a gap comprises providing a gap that is asymmetric relative to at least one transverse axis.

67. The method of claim 62, wherein the step of determining a gap comprises providing a gap that is defined at least by an indentation that extends into at least one of the first conductor and the second conductor.

68. The method of claim 67, wherein the indentation is a notch.

69. The method of claim 67, wherein the indentation is curved.

70. The method of claim 62, wherein the step of determining a gap comprises providing a gap that is defined at least by a protrusion that extends from at least one of the first conductor and the second conductor.

71. The method of claim 70, wherein the protrusion has an angled shape.

72. The method of claim 70, wherein the protrusion is curved.

73. The method of claim 62, further segmenting at least one of the first conductor and the second conductor into more than two sections to further define the pattern.

74. The method of claim 73, the step of segmenting comprises applying a layer of at least one dielectric material to at least one of the first conductor and the second conductor, the layer providing varying impedance.

75. The method of claim 62, further comprises applying a layer of at least one dielectric material to at least one of the first conductor and the second conductor, the layer providing varying impedance.

76. The method of claim 62, wherein the step of determining a gap comprises providing a gap defined by the first conductor and the second conductor being substantially planar and parallel to each other.

77. The method of claim 62, wherein the first conductor is an outer conductor having an interior surface defining a longitudinal interior passageway;

and the second conductor is an inner conductor positioned within the interior passageway of the outer conductor.

78. The method of claim 77, wherein the step of determining a gap comprises providing a non-annular gap between the inner conductor and the outer conductor.

79. The method of claim 77, wherein the step of determining a gap comprises providing a gap having a varying thickness defined by more than one distance between the exterior surface of the inner conductor and the interior surface of the outer conductor.

80. The method of claim 62, wherein the application end includes an eye contact portion configured to apply the energy to an eye feature and providing a reshaping mold to reshape the eye feature as the eye feature responds to the application of the energy.

81. The method of claim 62, wherein the positioning system comprises a vacuum fixation device creating a vacuum connection with an eye and to position the energy conducting element relative to the eye, whereby the energy conducting element directs the energy to the eye.

82. The method of claim 62, further comprising replacing the application end with one of a plurality of removably attachable end pieces.

83. A method for applying therapy to an eye with a conducting assembly comprising an energy conducting element including a first conductor and a second conductor, the first conductor and the second conductor extending to an application end and being separated by a gap;

and one or more materials providing varying impedance, the one or more materials being applied, at the application end, to at least one of the first conductor and the second conductor, the first conductor and the second conductor conducting energy to the eye via the application end at least according to a pattern defined by the varying impedance, the method comprising;

positioning the application end of the conducting assembly at an eye; and

reshaping an eye feature by applying energy to the eye via the conducting element according to the varying impedance. reshaping an eye feature by applying energy to the eye via the conducting element according to a pattern, the pattern being defined at least by the one or more materials and the position of the application end relative to the eye feature.

84. The method of claim 83, wherein the one or more materials includes a material applied in layers of varying thickness to provide varying impedance.

85. The method of claim 83, wherein the one or more materials includes materials that provide varying impedance for a given applied thickness.

86. The method of claim 83, wherein the pattern for conducting energy is asymmetric.

87. The method of claim 83, wherein the pattern for conducting energy is non-annular.

88. The method of claim 83, wherein the pattern for conducting energy is substantially elliptical.

89. The method of claim 83, wherein the varying impedance includes at least one area of high impedance preventing conduction of energy therefrom and at least one area of low impedance allowing conduction of energy therefrom, the areas of high impedance and the areas of low impedance defining the pattern for conducting energy via the application end.

90. The method of claim 89, wherein the at least one area of low impedance includes at least one protrusion extending into the gap.

91. The method of claim 89, wherein the at least one area of low impedance includes at least one indentation extending from the gap.

92. The method of claim 83, wherein the gap is non-annular.

93. The method of claim 83, wherein the gap is asymmetric.

94. The method of claim 83, wherein the gap includes a protrusion.

95. The method of claim 83, wherein the gap includes an indentation.

96. The method of claim 83, wherein the first conductor is an outer conductor having an interior surface defining a longitudinal interior passageway;

and the second conductor is an inner conductor positioned within the interior passageway of the outer conductor.

97. The method of claim 83, wherein the positioning system comprises a vacuum fixation device creating a vacuum connection with an eye and to position the energy conducting element relative to the eye, whereby the energy conducting element directs the energy to the eye.

98. The method of claim 83, further comprising replacing the application end with one of a plurality of removably attachable end pieces.