TRANSDERMAL DELIVERY OF OPTICAL, SPECT, MULTIMODAL, DRUG OR BIOLOGICAL CARGO LADEN NANOPARTICLE(S) IN SMALL ANIMALS OR HUMANS
First Claim
1. A method for transdermal delivery of biological cargo-laden nanoparticles, said particles including multimodal optical molecular imaging probes, to an animal or human, comprising steps of:
- providing the biological cargo-laden nanoparticles in a form that can be absorbed through the skin; and
delivering said biological cargo-laden nanoparticles to said skin of an animal or human.
6 Assignments
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Accused Products
Abstract
A method and a device are disclosed for transdermal delivery to an animal or human of biological cargo-laden nanoparticles. The particles may include multimodal optical molecular imaging probes. The particles may be delivered by providing them in a form that can be absorbed through the skin and applying them to the skin of an animal or human. The application may be accomplished using biological cargo-laden nanoparticles in a device attachable to the skin. The device may be attached directly to the skin by a device containing a vasodilating agent or agents, or micro needles, or multi-layer time release material. The biological cargo-laden nanoparticles may comprise drugs, vaccines, bio-pharmaceuticals, imaging contrast agents, multimodal imaging contrast agents, biomolecules, or anti-infectives. The device may include a first plurality of different types of biological cargo-laden nanoparticles located in a corresponding second plurality of separate time release layers.
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Citations
28 Claims
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1. A method for transdermal delivery of biological cargo-laden nanoparticles, said particles including multimodal optical molecular imaging probes, to an animal or human, comprising steps of:
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providing the biological cargo-laden nanoparticles in a form that can be absorbed through the skin; and delivering said biological cargo-laden nanoparticles to said skin of an animal or human. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A device for transdermal delivery of biological cargo to an animal or human, comprising:
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biological cargo-laden nanoparticles, said particles including multimodal optical molecular imaging probes, in a form that can be absorbed through the skin, and a device attachable to said skin for delivering said biological cargo-laden nanoparticle(s) to said skin of an animal or human. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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Specification