STENT WITH TABS AND HOLES FOR DRUG DELIVERY

• US 20090281615A1
• Filed: 05/08/2008
• Published: 11/12/2009
• Est. Priority Date: 05/08/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Inventors: Gregorich, Daniel, Girton, Timothy S., Kocur, Gordon J.
• Granted Patent: US 8,114,151 B2
• Time in Patent Office: Days
• US Class Current: 623/1.160
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir

Abstract

A stent can include a tubular body, a plurality of circumferential serpentine bands, a plurality of connectors extending between immediately adjacent serpentine bands, and a plurality of tabs. The plurality of tabs include peak tabs and trough tabs. Each peak tab and each trough tab have a first end and a second end wherein only the first end is engaged to a serpentine band, each peak tab extends substantially parallel to the longitudinal axis from a peak on a serpentine band toward a peak on an immediately distal serpentine band. Each trough tab extends substantially parallel to the longitudinal axis from a trough on a serpentine band toward a trough on an immediately proximal serpentine band. Each serpentine band defines a plurality of holes and each tab defines a plurality of holes. The holes are constructed and arranged to contain a therapeutic agent

Claims

1. A stent comprising:

a generally tubular body disposed about a longitudinal axis, the stent having a proximal end and a distal end;

a plurality of circumferential serpentine bands, each serpentine band having alternating peaks and troughs, each serpentine band having a wavelength and an amplitude, the peaks of each serpentine band being substantially aligned with the peaks of each immediately adjacent serpentine band;

a plurality of connectors, the connectors extending between immediately adjacent serpentine bands; and

a plurality of tabs, the plurality of tabs comprising peak tabs and trough tabs, each peak tab and each trough tab having a first end and a second end wherein only the first end is engaged to a serpentine band, each peak tab extending substantially parallel to the longitudinal axis from a peak on a serpentine band toward a peak on an immediately distal serpentine band, each trough tab extending substantially parallel to the longitudinal axis from a trough on a serpentine band toward a trough on an immediately proximal serpentine band,

wherein each serpentine band defines a plurality of holes, each hole on a serpentine band being located approximately a distance D₁ from each immediately adjacent hole on the serpentine band, and

wherein each tab defines a plurality of holes, each hole on a tab being located approximately distance D₂ from each immediately adjacent hole on the tab, the holes constructed and arranged to contain a therapeutic agent.

2. The stent of claim 1, wherein D₁ is substantially equal to D₂.

3. The stent of claim 1, wherein D₁ is greater than D₂.

4. The stent of claim 1, wherein D₁ is less than D₂

5. The stent of claim 1, wherein each of the plurality of connectors extends from a trough on a serpentine band to a trough on an immediately proximal serpentine band

6. The stent of claim 1, wherein at least one of the plurality of tabs has a connected end and an unconnected end, and a first side and a second side, the first side and the second side extending between the connected end and the unconnected end, the first side and the second side defining a width therebetween, the width being substantially constant along the length of the tab

7. The stent of claim 1, wherein at least one of the plurality of tabs has a connected end, an unconnected end, and a first side and a second side, the first side and the second side extending between the connected end and the unconnected end, the first side and the second side defining a width therebetween, the width being variable along the length of the tab, the at least one of the plurality of tabs comprising a first portion having a first width and a second portion having a second width, the second width being greater than the first width.

8. The stent of claim 7, wherein the at least one hole is positioned in the second portion.

9. The stent of claim 8, wherein the at least one of the plurality of tabs comprises a longitudinal axis, the at least one hole having a center off of the longitudinal axis.

10. The stent of claim 1, wherein each of the plurality of serpentine bands has the same wavelength and amplitude.

11. The stent of claim 1, wherein each of the plurality of serpentine bands has the same amplitude

12. The stent of claim 1, wherein each of the plurality of serpentine bands has the same wavelength.

13. The stent of claim 1, wherein each of the plurality of tabs has substantially the same length.

14. A stent comprising:

a generally tubular body disposed about a longitudinal axis, the stent having a proximal end and a distal end;

a plurality of circumferential serpentine bands, each serpentine band having alternating peaks and troughs, each serpentine band comprising a plurality of struts, each serpentine band having a wavelength and an amplitude, the peaks of each serpentine band being substantially aligned with the troughs of each immediately adjacent serpentine band;

a plurality of connectors, the connectors extending between immediately adjacent serpentine bands; and

a plurality of tabs, the plurality of tabs comprising peak tabs and trough tabs, each peak tab extending substantially parallel to the longitudinal axis from a peak on a serpentine band toward a trough on an immediately proximal serpentine band, each trough tab extending substantially parallel to the longitudinal axis from a trough on a serpentine band toward a peak on an immediately distal serpentine band,

wherein at least one of the plurality of struts defines at least one hole, and at least one of the plurality of tabs defines at least one hole, the at least one hole constructed and arranged to contain a therapeutic agent.

15. The stent of claim 14, wherein at least one of the plurality of connectors includes a hole

16. The stent of claim 14, wherein at least one of the plurality of connectors includes a curved region.

17. A stent comprising:

a generally tubular body disposed about a longitudinal axis, the stent having a proximal end and a distal end;

a plurality of circumferential serpentine bands, each serpentine band having alternating peaks and troughs, each serpentine band comprising a plurality of struts, each serpentine band having a wavelength and an amplitude, the peaks of each serpentine band being substantially aligned with the peaks of each immediately adjacent serpentine band, each peak having a proximal surface and a distal surface, each trough having a proximal surface and distal surface, the distal surface of the peaks of a serpentine band defining a peak circumferential plane, the proximal surface of the troughs of a serpentine band defining a trough circumferential plane;

a plurality of connectors, the connectors extending between immediately adjacent serpentine bands; and

at least one circumferential tab column, the at least one tab column being defined by the peak circumferential plane of a serpentine band and the trough circumferential plane of an immediately distal serpentine band,

the at least one tab column comprising a plurality of tabs, the plurality of tabs comprising peak tabs and trough tabs, each peak tab extending substantially parallel to the longitudinal axis from a peak on a serpentine band toward a peak on an immediately distal serpentine band, each trough tab extending substantially parallel to the longitudinal axis from a trough on a serpentine band toward a trough on an immediately proximal serpentine band,

wherein at least one of the plurality of struts defines at least one hole, and at least one of the plurality of tabs defines at least one hole, the at least one hole constructed and arranged to contain a therapeutic agent

18. The stent of claim 17, wherein the proximal surface of the peaks of a serpentine band defines an inner peak circumferential plane, and wherein the distal surface of the troughs of a serpentine band defines an inner trough circumferential plane, and wherein the peak tabs extend distally no further than the inner trough circumferential plane

19. The stent of claim 18, wherein the trough tabs extend proximally no further than the inner peak circumferential plane.