POLYMER COMPOSITIONS, COATINGS AND DEVICES, AND METHODS OF MAKING AND USING THE SAME
First Claim
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1. A biocompatible, thromboresistant coating for use on an implantable medical device, comprising:
- a chalcogenide compound that induces nitric oxide formation; and
a biocompatible matrix incorporating said chalcogenide compound.
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Abstract
The disclosure provides for a biocompatible, thromboresistant coating including a chalcogenide compound that induces nitric oxide formation; and a biocompatible matrix incorporating the chalcogenide compound. Devices incorporating such coatings, and methods of making and using such coatings are also disclosed herein.
120 Citations
43 Claims
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1. A biocompatible, thromboresistant coating for use on an implantable medical device, comprising:
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a chalcogenide compound that induces nitric oxide formation; and a biocompatible matrix incorporating said chalcogenide compound. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 28, 29, 30, 31, 32, 33, 34, 35, 36, 39, 40, 41, 42)
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21. A composition for use in association with a bioimplant, the composition comprising a matrix covalently bound to a chalcogenide moiety;
- wherein said chalcogenide moiety is selected from an organoselenium moiety and an organotellurium moiety.
- View Dependent Claims (22, 23, 24, 25, 26, 27, 37, 38)
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43-44. -44. (canceled)
Specification