ANALYTE SENSOR
First Claim
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1. A system for monitoring analyte concentration in a biological fluid of a host, the system comprising:
- an analyte sensor configured to produce a data signal indicative of an analyte concentration in a host during exposure of the sensor to a biological fluid;
a vascular access device configured for communication with a circulatory system of a host, wherein the vascular access device comprises a catheter configured for insertion into the host'"'"'s circulatory system and tubing;
a high oxygen solubility material that has at least about 3×
higher oxygen solubility than aqueous media;
a infusion solution, wherein the oxygen concentration of the infusion solution is greater than the oxygen concentration of the biological fluid; and
a flow control device configured to intermittently expose the sensor to the biological fluid and to the infusion solution, wherein the flow control device is configured to draw back the biological fluid into the catheter but not substantially into the tubing during a first phase, and to infuse the infusion solution through the catheter into the host during a second phase.
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Abstract
Systems and methods of use for continuous analyte measurement of a host'"'"'s vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host'"'"'s circulatory system.
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Citations
22 Claims
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1. A system for monitoring analyte concentration in a biological fluid of a host, the system comprising:
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an analyte sensor configured to produce a data signal indicative of an analyte concentration in a host during exposure of the sensor to a biological fluid; a vascular access device configured for communication with a circulatory system of a host, wherein the vascular access device comprises a catheter configured for insertion into the host'"'"'s circulatory system and tubing; a high oxygen solubility material that has at least about 3×
higher oxygen solubility than aqueous media;a infusion solution, wherein the oxygen concentration of the infusion solution is greater than the oxygen concentration of the biological fluid; and a flow control device configured to intermittently expose the sensor to the biological fluid and to the infusion solution, wherein the flow control device is configured to draw back the biological fluid into the catheter but not substantially into the tubing during a first phase, and to infuse the infusion solution through the catheter into the host during a second phase. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification