Circulatory monitoring systems and methods

• US 20090287094A1
• Filed: 05/15/2008
• Published: 11/19/2009
• Est. Priority Date: 05/15/2008
• Status: Abandoned Application

• Current Assignee: Searete LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC A Limited Liability Corporation of The State of Delaware
• Inventors: Ishikawa, Muriel Y., Ferren, Bran, Wood, Lowell L. JR., Rivet, Dennis J., Hyde, Roderick A., Wood, Victoria Y.H., Leuthardt, Eric C., Hagen, Jeffrey John
• Application Number:
  US12/152,868
• Publication Number:
  US 20090287094A1
• Time in Patent Office: Days
• US Class Current: 600/481
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/412 Detecting or monitoring sepsis
• CPC Class Codes: A61B 5/415 the glands, e.g. tonsils, adenoids or thymus
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes

Abstract

Systems and methods are described for obtaining and acting upon information indicative of circulatory health and related phenomena in human beings or other subjects.

Claims

1. A medical or veterinary system comprising:

a first artificial structure configured to administer a therapeutic material containing at least dioxygen and an artificial component locally to a treatment site via one or more capillaries of a vasculature of a subject.

2. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a fluid-bearing conduit; and

one or more reservoirs configured to dispense the therapeutic material into the fluid-bearing conduit.

3. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a conduit long enough to extend into a position within the vasculature and local to a vital organ of the subject.

4. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a conduit long enough to extend into a venous or venular dispensation position local to a vital organ of the subject.

5. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a conduit containing a portion of the therapeutic material and extending at least into a vein.

6. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a pump configured to control at least one flow into the vasculature of the subject.

7. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

circuitry for generating a timestamp within a few minutes of one or more events in the first artificial structure.

8. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

the therapeutic material, in which at least some of the dioxygen is bound to one or more of hemoglobin or perfluoroheptane.

9. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

the artificial component, containing one or more of an antineoplastic agent or a toxin.

10. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

the artificial component, containing one or more of a hormone or a nitric oxide source.

11. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

an inlet configured to receive blood from within the vasculature.

12. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

one or more actuators configured to cause an injection of the therapeutic material into the vasculature.

13. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

an in-dwelling catheter.

14. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

circuitry for detecting one or more components of the therapeutic material in the vasculature.

15. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

circuitry for recording one or more samples of sensor data.

16. The medical or veterinary system of claim 1, further comprising:

circuitry for triggering an actuation of an artificial occlusion structure.

17. The medical or veterinary system of claim 1, further comprising:

a clamp configured to limit a blood flow in the vasculature.

18. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a dispensation actuator configured to allow a dispensation of the therapeutic material in response to one or more of a force change, a pressure change, or a flow change.

19. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

circuitry for detecting a pressure during a dispensation of the therapeutic material.

20. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

circuitry for detecting a flow volume during a dispensation of the therapeutic material.

21. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

circuitry for detecting a position during a dispensation of the therapeutic material.

22. The medical or veterinary system of claim 1 in which the first artificial structure comprises:

a sensor configured to monitor one or more physical phenomena during a dispensation of the therapeutic material.

23. The medical or veterinary system of claim 1, further comprising:

a disposal operable for receiving a portion of the therapeutic material from the vasculature.

24. The medical or veterinary system of claim 1, further comprising:

a second artificial structure configured to receive a flow from the vasculature.

25. The medical or veterinary system of claim 1, further comprising:

one or more elements configured to filter a blood flow of the subject.

26. The medical or veterinary system of claim 1, further comprising:

another artificial structure configured to position a portion of the first artificial structure in a vicinity of an organ comprising the treatment site.

27. The medical or veterinary system of claim 1, further comprising:

an imaging apparatus configured to facilitate positioning a distal portion of the first artificial structure locally to and upstream from the treatment site.

28. The medical or veterinary system of claim 1, further comprising:

circuitry for obtaining local respiratory-status-indicative information relating to the treatment site.

29. The medical or veterinary system of claim 1, further comprising:

circuitry for obtaining an image of at least a portion of the treatment site.

52. The medical or veterinary system of claim 24 in which the first artificial structure comprises:

an inlet configured to receive blood from within the vasculature;

the artificial component, containing one or more of an antineoplastic agent, a toxin, a hormone, or a nitric oxide source;

a conduit long enough to extend into a venous or venular dispensation position local to a vital organ of the subject;

a dispensation actuator configured to allow a dispensation of the therapeutic material in response to one or more of a force change, a pressure change, or a flow change; and

circuitry for detecting a flow volume, a position, and a pressure during the dispensation of the therapeutic material.

30-51. -51. (canceled)