ATRAUMATIC PROSTHETIC HEART VALVE PROSTHESIS
First Claim
1. A heart valve prosthesis adapted for minimally invasive delivery to an implantation site of a patient, the implantation site having an annulus, a Valsalva sinus, and an aortic tunica intima, the prosthesis comprising:
- an anchoring structure having a radially collapsed configuration for delivery and a radially expanded configuration for deployment;
a valve coupled to the anchoring structure and configured such that in the expanded configuration, the valve permits blood flow through the lumen in a first direction and substantially prevents blood flow through the lumen in a second direction generally opposite the first direction;
wherein the anchoring structure includes a generally cylindrical portion adapted to engage an annular vessel wall at the implantation site;
wherein the generally cylindrical portion includes an outflow portion adapted to engage the vessel wall at a location distal to the Valsalva sinus; and
wherein, in the expanded configuration, the outflow portion tapers inwardly towards a distal end, such that the distal end imparts less force than a proximal portion upon the aortic tunica intima.
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Accused Products
Abstract
An atraumatic heart valve prosthesis includes a prosthetic valve coupled to an expandable anchoring structure including a outflow portion configured to taper inwardly in a distal direction towards a central axis of the prosthesis. By this configuration, the distal end of the anchoring structure imparts less force upon the vessel wall (e.g., the aortic tunica intima) during continued expansion and contraction of the heart. The expandable anchoring structure can be balloon expandable or self-expanding.
406 Citations
20 Claims
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1. A heart valve prosthesis adapted for minimally invasive delivery to an implantation site of a patient, the implantation site having an annulus, a Valsalva sinus, and an aortic tunica intima, the prosthesis comprising:
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an anchoring structure having a radially collapsed configuration for delivery and a radially expanded configuration for deployment; a valve coupled to the anchoring structure and configured such that in the expanded configuration, the valve permits blood flow through the lumen in a first direction and substantially prevents blood flow through the lumen in a second direction generally opposite the first direction; wherein the anchoring structure includes a generally cylindrical portion adapted to engage an annular vessel wall at the implantation site; wherein the generally cylindrical portion includes an outflow portion adapted to engage the vessel wall at a location distal to the Valsalva sinus; and wherein, in the expanded configuration, the outflow portion tapers inwardly towards a distal end, such that the distal end imparts less force than a proximal portion upon the aortic tunica intima. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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- 8. A heart valve prosthesis configured for delivery to an implantation site in a minimally invasive manner, the prosthesis comprising an expandable anchoring structure having a concave, tapered outflow portion configured to minimize damage to the aortic tunica intima.
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18. A heart valve prosthesis adapted for minimally invasive delivery to an implantation site of a patient, the implantation site having an annulus, a Valsalva sinus, and an aortic tunica intima, the prosthesis comprising an expandable stent structure sized and shaped to prevent a locus minoris resistentiae in an aortic wall when the prosthesis is balloon expanded.
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19. A system for delivering a heart valve prosthesis to an implantation site within a patient'"'"'s heart and implanting the prosthesis at the implantation site, the system comprising:
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an implantation catheter; and an expandable stent and valve, the stent selected from the group consisting of a balloon-expandable stent and a self-expandable stent, the stent having a first portion for supporting the valve and a second portion opposite the first portion, the second portion dimensioned to minimize damage to the aortic tunica intima caused by repeated expansion and contraction of the heart after implantation - View Dependent Claims (20)
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Specification