SYSTEM AND METHOD FOR GENERATING MR MYOCARDIAL PERFUSION MAPS WITHOUT USER INTERACTION
First Claim
Patent Images
1. A method of automatically generating a myocardial perfusion map from a sequence of magnetic resonance (MR) images, said method comprising the steps of:
- determining a region of interest (ROI) in a reference frame selected from a time series of myocardial perfusion MR image slices;
registering each image slice in said time series of slices to the reference frame to obtain a series of registered ROIs; and
using the series of registered ROIs to segment endo- and epi-cardial boundaries of a myocardium in the ROI.
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Abstract
A method for automatically generating a myocardial perfusion map from a sequence of magnetic resonance (MR) images includes determining a region of interest (ROI) in a reference frame selected from a time series of myocardial perfusion MR image slices, registering each image slice in the time series of slices to the reference frame to obtain a series of registered ROIs, and using the series of registered ROIs to segment endo- and epi-cardial boundaries of a myocardium in the ROI.
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26 Claims
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1. A method of automatically generating a myocardial perfusion map from a sequence of magnetic resonance (MR) images, said method comprising the steps of:
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determining a region of interest (ROI) in a reference frame selected from a time series of myocardial perfusion MR image slices; registering each image slice in said time series of slices to the reference frame to obtain a series of registered ROIs; and using the series of registered ROIs to segment endo- and epi-cardial boundaries of a myocardium in the ROI. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of automatically generating a myocardial perfusion map from a sequence of magnetic resonance (MR) volumetric images, said method comprising the steps of:
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providing a time series of registered myocardial perfusion MR image slices having reference image with a masked left ventricle (LV); detecting the right ventricle (RV) in the reference frame and estimating a thickness of the myocardium based on the detected LV and RV; initializing the endo-cardium and epi-cardium boundaries from the LV mask and myocardial thickness estimate; segmenting the endo-cardium by minimizing an energy functional; masking out a left-ventricle (LV) blood pool inside of the endo-cardium from the image series, and segmenting the epi-cardium by minimizing another energy functional, wherein each said energy functional incorporates correlation information among pixels in a same slice as well as temporal correlations across the slices in the time series, prior shape information and anatomical constraints. - View Dependent Claims (14)
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15. A program storage device readable by a computer, tangibly embodying a program of instructions executable by the computer to perform the method steps for automatically generating a myocardial perfusion map from a sequence of magnetic resonance (MR) images, said method comprising the steps of:
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determining a region of interest (ROI) in a reference frame selected from a time series of myocardial perfusion MR image slices; registering each image slice in said time series of slices to the reference frame to obtain a series of registered ROIs; and using the series of registered ROIs to segment endo- and epi-cardial boundaries of a myocardium in the ROI. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
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Specification