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Allograft osteochondral plug combined with cartilage particle mixture

  • US 20090291112A1
  • Filed: 02/09/2009
  • Published: 11/26/2009
  • Est. Priority Date: 05/16/2003
  • Status: Abandoned Application
First Claim
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1. In combination, a mixture including lyophilized, freeze-milled cartilage particles, at least a majority of which have a dimension, when dry, that does not exceed 212 microns;

  • and a sterile allograft osteochondral plug, said plug including a subchondral bone portion and an integral overlying cartilage cap which has been treated to remove cellular debris, chondrocytes and proteoglycans, at least a portion of said plug having a lateral dimension selected to form an interference fit against a tissue layer exposed as a result of a bore formed in a defect area in articular cartilage of a host, wherein said cartilage particle mixture is placed adjacent at least a portion of said plug for promoting cartilage cell migration into and proliferation in the bore and for enhancing tissue integration between said plug and host tissue, when said plug is inserted into the bore.

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