CHITOSAN-CONTAINING PROTECTIVE COMPOSITION
First Claim
1. A two-part composition, the first part comprising a partially crosslinked polysaccharide and the second part comprising a further crosslinker for the polysaccharide, wherein the polysaccharide or further crosslinker comprise chitosan or a chitosan derivative and the composition when hydrated and mixed can be delivered as a fluid through a spray applicator to provide a thin, conformal protective layer on a body temperature substantially vertical skin surface.
5 Assignments
0 Petitions
Accused Products
Abstract
Body tissue and structures may be protected using a fluid containing a mixture of partially crosslinked polysaccharide and a further crosslinker. The mixture desirably is sprayable, forms a fluid protective layer via in situ crosslinking, desirably does not drip or run from a treatment site, and may avoid the use of more rapidly curing but potentially less bioacceptable crosslinkers at the treatment site.
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Citations
15 Claims
- 1. A two-part composition, the first part comprising a partially crosslinked polysaccharide and the second part comprising a further crosslinker for the polysaccharide, wherein the polysaccharide or further crosslinker comprise chitosan or a chitosan derivative and the composition when hydrated and mixed can be delivered as a fluid through a spray applicator to provide a thin, conformal protective layer on a body temperature substantially vertical skin surface.
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14. A protective layer on a body temperature surface, the layer comprising an initially fluid mixture of a partially crosslinked polysaccharide and a further crosslinker for the polysaccharide, wherein the polysaccharide or further crosslinker comprise chitosan or a chitosan derivative and the partially crosslinked polysaccharide was partially crosslinked before mixture with the further crosslinker.
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15. A method for treating body tissue or structure, which method comprises:
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a) mixing a two-part composition, the first part comprising a partially crosslinked polysaccharide solution and the second part comprising a further crosslinker for the polysaccharide, wherein the polysaccharide or further crosslinker comprise chitosan or a chitosan derivative; b) applying the mixed parts as a fluid directed onto the body tissue or structure to form a protective layer thereon.
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Specification