HYBRID BIOELECTRICAL INTERFACE DEVICE
First Claim
1. A hybrid bioelectrical interface device for interfacing living neural tissue with electronic devices comprising:
- an abiotic component operable to transmit charge via electrons or ions;
a biological component interfacing with the neural tissue, said biological component being sourced from biologic, biologically-derived, or bio-functionalized material; and
a conjugated polymer component interfacing said abiotic component and said biological component, said conjugated polymer component promoting electronic to ionic charge transfer between said abiotic and biological components.
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Abstract
A hybrid bioelectrical interface (HBI) device can be an implantable device comprising an abiotic component operable to transmit charge via electrons or ions; a biological component interfacing with the neural tissue, the biological component being sourced from biologic, biologically-derived, or bio-functionalized material; and a conjugated polymer component that together provide a means to chronically interface living neural tissue with electronic devices for extended durations (e.g. greater than 10 years). In some embodiments, conjugated polymers provide a functional electrical interface for charge transfer and signal transduction between the nervous system and an electronic device (e.g. robotic prosthetic limb, retinal implant, microchip).
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Citations
15 Claims
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1. A hybrid bioelectrical interface device for interfacing living neural tissue with electronic devices comprising:
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an abiotic component operable to transmit charge via electrons or ions; a biological component interfacing with the neural tissue, said biological component being sourced from biologic, biologically-derived, or bio-functionalized material; and a conjugated polymer component interfacing said abiotic component and said biological component, said conjugated polymer component promoting electronic to ionic charge transfer between said abiotic and biological components. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An implantable hybrid bioelectrical interface device for interfacing living neural tissue with electronic devices comprising:
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an abiotic component operable to transmit charge via electrons or ions; a biological component interfacing with the neural tissue, said biological component being biologic, biologically-derived, or bio-functionalized; a conjugated polymer scaffold interfacing said abiotic component and said biological component, said conjugated polymer scaffold promoting electronic to ionic charge transfer between said abiotic and biotic components; and a housing having an electrolyte, said housing substantially surrounding at least a portion of said biological component, said conjugated polymer scaffold and said abiotic component. - View Dependent Claims (10, 11, 12, 13, 14)
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15. A hybrid bioelectrical interface (HBI) device comprising:
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an abiotic component operable to transmit charge via electrons or ions; a acellularized tissue disposed at least partially on said abiotic component; a conjugated polymer scaffold disposed at least partially within said biological component or at least partially covering said biological component; and a housing comprising a polymer or a hydrogel material, said housing having a proximal end and a distal end, said housing covering at least a portion of at least one of said abiotic component, said acellularized tissue and said conjugated polymer scaffold.
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Specification