Methods and Systems for Treating BPH Using Electroporation
First Claim
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1. A system for treating benign prostate hyperplasia (BPH) of a prostate, comprising:
- at least two electrodes configured to be introduced near a BPH tissue site of a patient;
a voltage pulse generator coupled to the electrodes and configured to apply a plurality of electrical pulses through the electrodes in an amount sufficient to produce irreversible electroporation of cells in the BPH tissue site to create necrosis of cells of the BPH tissue site but insufficient to create thermal damage to a majority of the BPH tissue site; and
a switching device coupled to the electrodes and the voltage pulse generator, and configured to activate the electrodes in a selected pattern.
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Abstract
A system for treating benign prostate hyperplasia (BPH) of a prostate. At least first and second mono-polar electrodes are configured to be introduced at or near a BPH tissue site of the prostate gland of the patient. A voltage pulse generator is coupled to the first and second mono-polar electrodes. The voltage pulse generator is configured to apply sufficient electrical pulses between the first and second mono-polar electrodes to induce electroporation of cells in the BPH tissue site, to create necrosis of cells of the BPH tissue site, but insufficient to create a thermal damaging effect to a majority of the BPH tissue site.
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Citations
22 Claims
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1. A system for treating benign prostate hyperplasia (BPH) of a prostate, comprising:
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at least two electrodes configured to be introduced near a BPH tissue site of a patient; a voltage pulse generator coupled to the electrodes and configured to apply a plurality of electrical pulses through the electrodes in an amount sufficient to produce irreversible electroporation of cells in the BPH tissue site to create necrosis of cells of the BPH tissue site but insufficient to create thermal damage to a majority of the BPH tissue site; and a switching device coupled to the electrodes and the voltage pulse generator, and configured to activate the electrodes in a selected pattern. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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12. A system for treating benign prostate hyperplasia (BPH) of a prostate, comprising:
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at least two electrodes configured to be introduced near a BPH tissue site of a patient; a voltage pulse generator coupled to the electrodes and configured to apply a plurality of electrical pulses through the electrodes in an amount sufficient to produce irreversible electroporation of cells in the BPH tissue site to create necrosis of cells of the BPH tissue site but insufficient to create thermal damage to a majority of the BPH tissue site; a switching device coupled to the electrodes and the voltage pulse generator; a controller containing software to control the switching device, the controller and the switching device together being configured to activate the electrodes in a selected pattern; and a user interface coupled to the controller for inputting the selected pattern.
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Specification