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SELF-PRESERVED EMULSIONS

  • US 20090298956A1
  • Filed: 05/27/2009
  • Published: 12/03/2009
  • Est. Priority Date: 05/28/2008
  • Status: Abandoned Application
First Claim
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1. An emulsion suitable for ocular, nasal or otic administration comprisingwater,a buffering agent,an oil,an emulsifier,a pH adjuster,a multifunctional synthetic compound of formula I, wherein:

  • x is 1 to 3 or mixtures thereof,x+y is equal to 3;

    a is 0 to 2;

    z is equal to x;

    B is O—

    or OM;

    A is an anion;

    M is a cation;

    Y is selected from the group consisting of OH, O—

    C1-C10 alkyl and O—

    C1-C10 alkenyl;

    andR1, R2 and R3 are the same or different and are alkyl, substituted alkyl, alkyl aryl or alkenyl groups, optionally interrupted by —

    NHC(═

    O)—

    , of up to 16 carbon atoms with the proviso that the total carbon atoms in R1+R1+R3 is between 10 and 24,and optionally a therapeutic agent.

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