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COMPOUNDS AND METHODS FOR MODULATING EXPRESSION APOB

  • US 20090306180A1
  • Filed: 05/07/2007
  • Published: 12/10/2009
  • Est. Priority Date: 05/05/2006
  • Status: Active Grant
First Claim
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1. A short antisense compound 8 to 16 monomers in length, comprising a 2′

  • -deoxyribonucleotide gap region flanked on each side by a wing, wherein each wing independently comprises 1 to 3 high-affinity modified monomers and wherein the short antisense compound is targeted to a nucleotide encoding ApoB.

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