STATE SPACE MODEL OF A HEART

• US 20090311656A1
• Filed: 07/06/2007
• Published: 12/17/2009
• Est. Priority Date: 07/25/2006
• Status: Active Grant

• Current Assignee: Gripping Heart AB
• Original Assignee: Gripping Heart AB
• Inventors: Lundback, Stig, Johnson, Jonas
• Granted Patent: US 8,244,510 B2
• Time in Patent Office: Days
• US Class Current: 434/262
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

A state space model (SSM), being a computer-calculated model, adapted to represent the pumping and controlling functions of a heart that have been determined by a heart cluster state machine simulating the heart, and optionally the circulatory system, of an individual. The state space model includes two groups of separate interacting state machines, the heart muscle cell state machines and the displacement pump state machines.

Claims

1. A state space model (SSM), being a computer-calculated model, adapted to represent the pumping and controlling functions of a heart that have been determined by a heart cluster state machine simulating the heart, and optionally the circulatory system, of an individual, characterized in that the state space model is adapted to transform all the muscular cell functions, except their volumes, to incomplete and/or complete wire frames and/or surface mesh models of the heart with impacts of the boundary conditions concerning the model and optionally the circulatory system, and that the state space model comprises two groups of separate interacting state machines, the heart muscle cell state machines and interactions of displacement pump state machines.

2. State space model according to claim 1, wherein the displacement pump state machines include an intra ventricular septum (IVS) state machine.

3. State space model according to claim 1, wherein the displacement pump state machines include DeltaV-pump state machines (DPSM).

4. State space model according to claim 1, wherein the heart muscle cell state machines comprise a main module describing the construction and boundary conditions of a working cardiac muscle cell and their interrelations on molecular and micro levels;

with an internal module, leaving the muscle cell volumes outside, describing the cardiac muscle cell functions on molecular and micro level including the conducting systems as construction material and power source with possibilities to be reluctant by elongation, firm by static work and create dynamic work by shortening, to be transferred to the contours and areas determined by the displacement pump state machines.

5. State space model according to claim 1, wherein the displacement pump state machines comprise a main module divided into sub modules schematically showing the construction of the heart as a geometric description of the heart in two and/or three dimensions as a mechanical device made by a fusion of two displacement pump state machines, e.g. DeltaV-pump state machines, creating the right and left side of the heart.

6. State space model according to claim 5, wherein the displacement pump state machines further comprise an Intra Ventricular Septum module (IVS) describing the constructions and functions of Intra Ventricular Septum as a result of the fusion of the two displacement pump state machines generating the third displacement pump state machine;

a Delta-V piston (DVP) module describing the construction and function of the Delta-V piston;

a RA-LA construction module describing the construction and functions of the right and left atria and auricle constructions, and a displacement pump state machine module consisting of lines, wire frames and/or surface mesh of outer contours and optionally the inner contours of the muscle volumes in one, two or three dimensions.

7. State space model according to claim 1, wherein the SSM is analyzed by a Heart State Analyzer (HSA) that can present these related data as e.g. discrete and/or dynamic state diagrams, optionally handled and organized by an Interconnecting Management System (IMS).

8. State space model according to claim 7, wherein a Graphical User Interface (GUI) module graphically presents e.g. one or several interacting discrete and/or dynamic time related state diagrams, optionally handled and organized by an Interconnecting Management System (IMS), obtained by (HSA) describing the pumping and regulating functions of the heart, and optionally the circulatory system.

9. State space model according to claim 1, wherein an Efficiency Rate Analyzer (ERA) module is connected to the SSM, optionally handled and organized by an Interconnecting Management System (IMS) to compare the outcome of the mechanical functions of the heart with the heart muscular rearrangements obtained by SSM, the ERA preferably may be used to present and optionally enhance the efficient rate of the muscles as construction material and power source.

10. State space model according to claim 1, wherein a Heart State Simulator (HSS) is connected to the SSM for learning purposes and to simulate the impacts that different kinds of boundary conditions changes will have on the modules of SSM, optionally handled and organized by an Interconnecting Management System (IMS).

11. State space model according to claim 8, wherein the SSM is arranged in a simple investigating device, e.g. a pressure sensor, a microphone, a photo sensor or a oxymeter, that also includes HSA and GUI, to create related data e.g. discrete and/or dynamic time related state diagrams.

12. State space model according to claim 7, used to create simple and fast investigating methods in one, two and/or three dimensions by mapping interacting points, contours and/or areas related to the pumping and regulating functions of the heart e.g. by dynamic triangular measurements calculated by HSA according to SSM, optionally handled and organized by an Interconnecting Management System (IMS).

13. State space model according to claim 8, wherein a Graphical User Interface (GUI) module graphically presents e.g. one or several interacting discrete and/or dynamic time related state diagrams, optionally handled and organized by an Interconnecting Management System (IMS), obtained by (HSA) describing the pumping and regulating functions of the heart, and optionally the circulatory system.