SYSTEM AND METHOD FOR DELIVERING ENERGY TO TISSUE

• US 20090312673A1
• Filed: 06/11/2009
• Published: 12/17/2009
• Est. Priority Date: 06/14/2008
• Status: Abandoned Application

• Current Assignee: VytronUS, Inc. (Johnson & Johnson)
• Original Assignee: VytronUS, Inc. (Johnson & Johnson)
• Inventors: Arenson, James W., Thapliyal, Hira V., Gallup, David A.
• Application Number:
  US12/482,640
• Publication Number:
  US 20090312673A1
• Time in Patent Office: Days
• US Class Current: 601/2
• CPC Class Codes: A61B 18/00 Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body eye surgery A61F9/007; ear surgery A61F11/00
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 18/08 by means of electrically-heated probes
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2018/00005 Cooling or heating of the probe or tissue immediately surrounding the probe
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00095 high, i.e. heat conducting
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00714 Temperature
• CPC Class Codes: A61B 2018/0212 using an instrument inserted into a body lumen, e.g. catheter
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2090/061 for measuring dimensions, e.g. length
• CPC Class Codes: A61N 2007/0073 using multiple frequencies
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

Methods and apparatus for treating a patient include an ablation device for treating atrial fibrillation. The device includes a housing having proximal and distal ends, and an energy source adjacent the distal end of the housing. The energy source has an active portion and an inactive portion. The active portion is adapted to deliver energy to tissue when the energy source is energized. This creates a partial or complete zone of ablation in the tissue that blocks abnormal electrical activity, thereby reducing or eliminating atrial fibrillation in the patient. The inactive portion does not emit energy or emits substantially no energy when the energy source is energized.

Claims

1. An ablation device for treating atrial fibrillation in a patient, said device comprising:

a housing having a proximal end and a distal end; and

an energy source adjacent the distal end of the housing, the energy source having an active portion and an inactive portion,

wherein the active portion is adapted to deliver energy to tissue when the energy source is energized thereby creating a partial or complete zone of ablation in the tissue that blocks abnormal electrical activity therethrough, reducing or eliminating atrial fibrillation in the patient, and

wherein the inactive portion does not emit energy or emits substantially no energy when the energy source is energized.

2. The device of claim 1, wherein the housing comprises an elongate shaft coupled with the proximal end of the housing.

3. The device of claim 1, wherein the energy source comprises an ultrasound transducer.

4. The device of claim 3, wherein the ultrasound transducer comprises a flat distal face.

5. The device of claim 3, wherein the ultrasound transducer comprises a concave or convex surface.

6. The device of claim 3, wherein the ultrasound transducer comprises a circular shape.

7. The device of claim 3, wherein the ultrasound transducer comprises a matching layer disposed on a front face thereof, the matching layer adapted reduce reflection of the energy emitted from the transducer back toward the transducer.

8. The device of claim 1, wherein the inactive portion of the energy source comprises an aperture in the energy source.

9. The device of claim 1, wherein the inactive portion of the energy source comprises a first material and the active portion comprises a second material different than the first material.

10. The device of claim 1, wherein the energy source comprises a plurality of inactive portions.

11. The device of claim 1, wherein the energy source comprises a plurality of annular transducers concentrically disposed around one another.

12. The device of claim 1, wherein the energy source comprises a grid of transducers.

13. The device of claim 1, wherein the energy source delivers one of radiofrequency energy, microwave energy, photonic energy, thermal energy, and cryogenic energy.

14. The device of claim 1, wherein the energy source delivers the energy in a beam, and the beam is positioned at an angle of between 40 degrees and 140 degrees relative to a surface of the tissue.

15. The device of claim 1, wherein the zone of ablation comprises a transmural lesion.

16. The device of claim 1, wherein the zone of ablation comprises a linear ablation path.

17. The device of claim 1, wherein the zone of ablation comprises a circular or elliptical ablation path.

18. The device of claim 1, wherein a distal end of the energy source is recessed from the distal end of the housing.

19. The device of claim 1, further comprising a sensor near the distal end of the housing.

20. The device of claim 19, wherein the sensor is adapted to detect distance between the energy source and a surface of the tissue.

21. The device of claim 19, wherein the sensor is adapted to detect characteristics of the tissue to be treated.

22. The device of claim 21, wherein the characteristics of the tissue comprise thickness of the tissue.

23. The device of claim 19, wherein the sensor comprises a temperature sensor.

24. The device of claim 1, further comprising a processor for controlling the energy source.

25. The device of claim 1, wherein the tissue comprises a pulmonary vein.

26. The device of claim 1, further comprising a coolant source having a coolant, wherein the coolant flows through the housing and cools the tissue.

27. The device of claim 19, further comprising a backing element coupled with the energy source, wherein the backing element provides a heat sink for the energy source.

28. The device of claim 27, wherein the backing element creates a reflective surface adapted to reflect energy from the energy source toward the distal end of the housing.

29. The device of claim 1, further comprising a lens coupled with the energy source and adapted to focus the beam of energy.

30. A method of ablating tissue in a patient as a treatment for atrial fibrillation, said method comprising:

providing a housing having a proximal end, a distal end, and an energy source adjacent the distal end;

energizing the energy source so that the energy source delivers energy to the tissue, wherein the energy source comprises an active portion and an inactive portion, and

wherein the active portion delivers the energy when the energy source is energized, and wherein the inactive portion does not emit energy or emits substantially no energy when the energy source is energized; and

creating a zone of ablation that blocks abnormal electrical activity in the tissue thereby reducing or eliminating atrial fibrillation in the patient.

31. The method of claim 30, wherein the energy source comprises an ultrasound transducer.

32. The method of claim 30, wherein the energy source delivers one of radiofrequency energy, microwave energy, photonic energy, thermal energy, and cryogenic energy to the tissue.

33. The method of claim 30, wherein the energy source comprises a first transducer and a second transducer, the method further comprising energizing the first transducer and energizing the second transducer, the first transducer being energized differently than the second transducer such that the first transducer emits a first energy beam different than a second energy beam emitted by the second transducer.

34. The method of claim 33, wherein the first transducer is operated in a therapeutic mode and wherein the second transducer is operated in a diagnostic mode.

35. The method of claim 30, wherein energizing the energy source comprises adjusting one of frequency, voltage, duty cycle, and power level of the energy delivered to the energy source.

36. The method of claim 30, wherein the energy delivered to the tissue has a frequency in the range of 5 to 25 MHz.

37. The method of claim 30, wherein the energy source is energized with a voltage ranging from 5 to 200 volts peak to peak.

38. The method of claim 30, wherein the zone of ablation comprises a transmural lesion.

39. The device of claim 30, wherein the zone of ablation comprises a linear ablation path.

40. The device of claim 30, wherein the zone of ablation comprises a circular or elliptical ablation path.

41. The method of claim 30, wherein creating the zone of ablation comprises rotating the energy source about an axis.

42. The method of claim 30, wherein the zone of ablation comprises a tear drop shaped region of the tissue.

43. The method of claim 30, wherein the zone of ablation has a depth of approximately 5 mm.

44. The method of claim 30, further comprising determining gap distance with a sensor coupled with the housing, the gap distance extending between the energy source and a surface of the tissue.

45. The method of claim 44, further comprising maintaining the gap distance substantially constant.

46. The method of claim 30, further comprising determining thickness of the tissue with a sensor coupled with the housing.

47. The method of claim 30, further comprising determining characteristics of the tissue with a sensor coupled with the housing.

48. The method of claim 47, wherein the sensor comprises a portion of the energy source.

49. The method of claim 30, further comprising sensing temperature of the tissue with a sensor coupled with the housing.

50. The method of claim 30, further comprising controlling the energy source with a processor.

51. The method of claim 30, wherein the tissue comprises a pulmonary vein.

52. The method of claim 30, further comprising positioning the housing in a left atrium of the patient'"'"'s heart.

53. The method of claim 30, further comprising adjusting an angle between the energy source and a surface of the tissue.

54. The method of claim 30, further comprising cooling the tissue thereby controlling shape of the ablation zone.

55. The method of claim 30, further comprising cooling the tissue thereby preventing damage to a portion of the tissue.

56. The method of claim 30, further comprising cooling the energy source.

57. The method of claim 54, wherein the step of cooling comprises cooling the tissue with a fluid that flows past the energy source.

58. The method of claim 30, further comprising controlling the shape of the zone of ablation.