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Methods for Detection of Circulating Tumor Cells and Methods of Diagnosis of Cancer in Mammalian Subject

  • US 20090317836A1
  • Filed: 01/30/2007
  • Published: 12/24/2009
  • Est. Priority Date: 01/30/2006
  • Status: Abandoned Application
First Claim
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1. A method for detecting circulating tumor cells in a mammalian subject suspected of having cancer comprising:

  • obtaining a test sample from blood of the subject, the test sample comprising a cell population,mounting the test sample on a substrate,detecting the presence or absence of a first marker in the test sample that selectively binds to the circulating tumor cells,detecting the presence or absence of a second marker in the test sample that binds to the cell population or a subset of the cell population, andanalyzing the cell population detected by the first and second markers to identify and characterize the circulating tumor cells.

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