COMBINATION OF AMINO ACID SOLUTION AND A GELATIN DERIVATIVE FOR INHIBITING RENAL UP-TAKE
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Abstract
The invention relates to a combination of a solution of a gelatin derivative and at least one amino acid, if desired in the form of a pharmaceutically acceptable salt or carboxylic acid derivative, for inhibiting renal uptake of substances, that are potentially damaging for the kidneys, in a living being.
1 Citation
28 Claims
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1-8. -8. (canceled)
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9. A method of preparing a composition for inhibiting renal uptake of a substance in a living being, comprising:
combining a solution of a gelatin derivative with at least one amino acid. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A therapeutic composition for the inhibition of renal uptake of substances that are potentially damaging for the kidneys and that are used for therapeutic or diagnostic purposes in a living being, comprising:
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a solution of a gelatin derivative; at least one amino acid; and at least one of a pharmaceutically acceptable excipient, carrier, diluent, and combinations thereof.
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20. A method of inhibiting renal uptake of a substance in a living being, comprising:
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preparing a composition, wherein the composition includes; a solution of a gelatin derivative; and a first amino acid, wherein the first amino acid is in the form of a pharmaceutically acceptable salt or carboxylic acid derivative; and administering the composition to the living being. - View Dependent Claims (21, 22, 23, 25, 27, 28)
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24. The method of claim 24, wherein the gelatin-based plasma expander is Gelofusine®
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26. The method of claim 26, wherein the synthetic colloidal solution of urea cross-linked degraded gelatin is Haemaccel®
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Specification