DETECTION OF CANCER MARKERS
First Claim
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1. A surface-molecularly imprinted sensor for detecting target biological molecules, the sensor comprising:
- a) an electrode; and
b) hydroxyl functionalized thio hydrocarbon chains directly assembled on the electrode, wherein the polymer monolayer or film is imprinted with cavities for detecting the target biological molecules.
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Abstract
The present invention relates to combining surface molecular imprinting (SMI) with the production of self-assembled monolayers (SAM) of hydroxyl alkanethiolate molecules on gold coated chip surfaces. In this technique, the sensing element is placed on the transducer and the whole assembly can then be miniaturized and integrated into a smart chip. These sensors can detect, nanomolar quantities of complex biomolecules.
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Citations
9 Claims
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1. A surface-molecularly imprinted sensor for detecting target biological molecules, the sensor comprising:
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a) an electrode; and b) hydroxyl functionalized thio hydrocarbon chains directly assembled on the electrode, wherein the polymer monolayer or film is imprinted with cavities for detecting the target biological molecules. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification