Medication Delivery Device

• US 20090318878A1
• Filed: 01/27/2006
• Published: 12/24/2009
• Est. Priority Date: 02/14/2005
• Status: Active Grant

• Current Assignee: Laboratoires Serono SA, Ares Trading SA (Merck & Co., Inc.)
• Original Assignee: Ares Trading SA (Merck & Co., Inc.)
• Inventors: Pongpairochana, Vincent, Piotelat, Sandrine, Chavez, Enrico
• Granted Patent: US 8,137,304 B2
• Time in Patent Office: Days
• US Class Current: 604/208
• CPC Class Codes: A61M 2005/31518 designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
• CPC Class Codes: A61M 2205/13 with means for the detection of operative contact with patient, e.g. lip sensor
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/2466 by piercing without internal pressure increase A61M5/2429 takes precedence

Abstract

The medication delivery device is designed to receive a replaceable medication container and to determine an adjusted medication dose AD before each delivery of the medication contained in the medication container if the current content of the medication container is not a multiple of a prescribed dose D and is greater than the prescribed dose D. The adjusted medication dose AD is the dose to be delivered instead of the prescribed dose D during said medication delivery. The adjusted medication dose AD is determined by selecting one of a first dose, to that is higher than the prescribed dose D, and of a second dose, that is lower than the prescribed dose D, as a function of a variable B that cumulates the values (AD−D).

Claims

1. A medication delivery device comprising means for receiving a replaceable medication container, a control unit and means, controlled by said control unit, for delivering at least one dose of the medication contained in said medication container to a patient, and means for determining an adjusted medication dose AD before each delivery of the medication contained in said medication container if the current content of the medication container is not a multiple of a prescribed dose D and is greater than the prescribed dose D, said adjusted medication dose AD being the dose to be delivered by said delivering means instead of the prescribed dose D during said medication delivery, said adjusted medication dose AD being determined by selecting one of a first dose, that is higher than the prescribed dose D, and of a second dose, that is lower than the prescribed dose D, as a function of a variable B that cumulates the values AD−

D.

2. The medication delivery device according to claim 1, wherein the adjusted medication dose AD is the one, among the first and second doses, for which the absolute value of the variable B is lower.

3. The medication delivery device according to claim 1, wherein the adjusted medication dose AD is equal to the first dose if the variable B is negative and is equal to the second dose if the variable B is positive.

4. The medication delivery device according to claim 1, wherein the first dose is equal to (Cont/n) and the second dose is equal to (Cont/(n+1)), where n is equal to INT (Cont/D) and Cont is the current content of the medication container.

5. The medication delivery device according to claim 1, wherein the first dose is equal to the minimum of (Cont/n) and at least one ceiling value and the second dose is equal to the maximum of (Cont/(n+1)) and at least one bottom value, where n is equal to INT (Cont/D) and Cont is the current content of the medication container.

6. The medication delivery device according to claim 5, wherein said at least one ceiling value includes the value (D+k.D) and said at least one bottom value includes the value (D−

k.D), where k is a predefined constant between 0 and 1.

7. The medication delivery device according to claim 1, including an electronic injection device designed to inject medication through the skin of a patient.

8. A method for determining medication doses, said method being performed by a control unit in a medication delivery device also comprising means for receiving a replaceable medication container and means, controlled by said control unit, for delivering at least one dose of the medication contained in said medication container to a patient, comprising the steps:

determining an adjusted medication dose AD before each delivery of the medication contained in said medication container if the current content of the medication container is not a multiple of a prescribed dose D and is greater than the prescribed dose D, said adjusted medication dose AD being the dose to be delivered by said delivering means instead of the prescribed dose D during said medication delivery, said adjusted medication dose AD being determined by selecting one of a first dose, that is higher than the prescribed dose D, and of a second dose, that is lower than the prescribed dose D, as a function of a variable B that cumulates the values AD−

D.

9. The method according to claim 8, wherein the adjusted medication dose AD is the one, among the first and second doses, for which the absolute value of the variable B is lower.

10. The method according to claim 8, wherein the adjusted medication dose AD is equal to the first dose if the variable B is negative and is equal to the second dose if the variable B is positive.

11. The method according to claim 8, wherein the first dose is equal to (Cont/n) and the second dose is equal to (Cont/(n+D), where n is equal to INT (Cont/D) and Cont is the current content of the medication container.

12. The method according to claim 8, wherein the first dose is equal to the minimum of (Cont/n) and at least one ceiling value and the second dose is equal to the maximum of (Cont/(n+D) and at least one bottom value, where n is equal to INT (Cont/D) and Cont is the current content of the medication container.

13. The method according to claim 12, wherein said at least one ceiling value includes the value (D+k.D) and said at least one bottom value includes the value (D−

k.D), where k is a predefined constant between 0 and 1.

14. A computer program executable by a control unit in a medication delivery device including means for receiving a replaceable medication container and means, controlled by said control unit, for delivering at least one dose of medication contained in said medication container to a patient, said code comprising an instructions code for performing the method defined in claim 8.