Systems, Methods and Apparatus for Treating Cardiac Dysfunction with Neurostimulation
First Claim
1. A method of treating a cardiac dysfunction in a human patient, the method comprising:
- positioning at least one neurostimulation device adjacent a nerve of the patient; and
delivering an electrical stimulation pulse to the nerve of the patient for a period of time sufficient to result in an alleviation of the cardiac dysfunction.
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Accused Products
Abstract
Methods, systems, and apparatus for the treatment of heart failure (both systolic and diastolic), hypertension, and arrhythmia in patients by stimulating one or more nerves, particularly peripheral nerves, using neurostimulation are described. The therapeutic treatment is accomplished by applying electrical signals to at least one or more nerves using cutaneous, subcutaneous, implantable, or catheter-based neurostimulation assemblies, alone or in combination with one or more additional therapy or stimulation devices associated with the patient'"'"'s heart, and/or with one or more therapeutic drug infusions or therapies, such as immune modulation therapy (IMT).
100 Citations
12 Claims
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1. A method of treating a cardiac dysfunction in a human patient, the method comprising:
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positioning at least one neurostimulation device adjacent a nerve of the patient; and delivering an electrical stimulation pulse to the nerve of the patient for a period of time sufficient to result in an alleviation of the cardiac dysfunction.
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2. A method of treating systolic heart failure in a patient, the method comprising:
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positioning at least one neurostimulation device adjacent a peripheral nerve of a patient; and delivering an electrical stimulation pulse to the peripheral nerve of the patient for a period of time sufficient to result in an alleviation of the systolic heart failure as indicated by decreased pulmonary resistance in the heart.
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3. A method of treating diastolic heart failure in a patient, the method comprising:
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positioning at least one neurostimulation device adjacent a peripheral nerve of a patient; and delivering an electrical stimulation pulse to the peripheral nerve of the patient for a period of time sufficient to result in an alleviation of the diastolic heart failure as indicated by decreased blood pressure in the heart.
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4. A method of treating arrhythmias in a patient, the method comprising:
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positioning at least one neurostimulation device adjacent a peripheral nerve of a patient; positioning at least one neurostimulation device adjacent a nerve in or near the brain of a patient; and delivering an electrical stimulation pulse to the peripheral nerve and the nerve near the brain of the patient for a period of time sufficient to result in an alleviation of the arrhythmia as indicated by decreased arterial fibrillation and/or ventricular fibrillation.
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5. A method of treating hypertension in a patient, the method comprising:
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positioning at least one neurostimulation device adjacent a peripheral nerve of a patient; positioning at least one neurostimulation device adjacent a nerve in or near the C2-C4 spinal region of a patient; and delivering an electrical stimulation pulse to the peripheral nerve and the nerve near the C2-C4 spinal region of the patient for a period of time sufficient to result in an alleviation of the hypertension as indicated by improved blood pressure control in the patient.
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6. A system for treating cardiac dysfunction in a patient, the system comprising:
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a device including a stimulator adapted to deliver a stimulation signal for a heart failure event; a plurality of sensors adapted to measure and provide information of a heart failure condition status at two separate times; and a controller in communication with the stimulator and the plurality of sensors and adapted to use the measurements from the sensors to control the stimulator to modulate the electrical signal. - View Dependent Claims (7, 8, 9, 10, 11)
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12. A system for treating cardiac dysfunction in a patient, the system comprising:
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means for applying an electrical stimulation to one or more nerves; means for measuring one or more indicators of heart failure status in a patient; means for monitoring the information obtained by the measurement means; and means for adjusting the intensity and rate of application of electrical impulses using the information obtained by the measurement means.
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Specification