OSMOTIC REACTION DETECTOR FOR MONITORING BIOLOGICAL AND NON-BIOLOGICAL REACTIONS
First Claim
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1. An osmotic cell system for monitoring reactivity in reactions between a first material of interest and a second material of interest, said osmotic cell system comprising:
- a first well for containing one of a reference solution and a reaction mixture comprising first and second materials of interest;
a second well for containing the other of the reference solution and the reaction mixture;
a semi-permeable membrane separating said first well from said second well; and
a pressure sensor for measuring changes in osmotic pressure in one of said first well and said second well after allowing said first and second wells to reach equilibrium.
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Abstract
A method and apparatus for measuring the presence or absence of reaction between a first and second material of interest by measuring osmotic pressure changes in a reaction cell. The reaction cell is capable of measuring the small changes in pressure that occur due to osmotic pressure shifts during a catalytic or binding reaction at species concentrations down to approximately 10−7 M.
25 Citations
21 Claims
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1. An osmotic cell system for monitoring reactivity in reactions between a first material of interest and a second material of interest, said osmotic cell system comprising:
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a first well for containing one of a reference solution and a reaction mixture comprising first and second materials of interest; a second well for containing the other of the reference solution and the reaction mixture; a semi-permeable membrane separating said first well from said second well; and a pressure sensor for measuring changes in osmotic pressure in one of said first well and said second well after allowing said first and second wells to reach equilibrium. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification