METHOD OF TREATING AUTOIMMUNE DISEASE WITH MESENCHYMAL STEM CELLS
First Claim
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1. A method of treating new onset type 1 diabetes (T1D) in a subject comprising administering autologous or allogeneic mesenchymal stem cells to the subject prior to autoimmune-induced complete depletion of insulin-producing pancreatic beta cells.
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Abstract
Methods and compositions for treating an autoimmune disease, such as new onset type 1 diabetes (T1D) in a subject using autologous or allogeneic mesenchymal stem cells administered to the subject prior to autoimmune-induced complete depletion of insulin-producing pancreatic beta cells, e.g., within six months of new onset type 1 diabetes (T1D) diagnosis or prior to the onset of disease in a subject determined to be at high risk for T1D.
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53 Claims
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1. A method of treating new onset type 1 diabetes (T1D) in a subject comprising administering autologous or allogeneic mesenchymal stem cells to the subject prior to autoimmune-induced complete depletion of insulin-producing pancreatic beta cells.
- 2. A method of treating new onset type 1 diabetes (T1D) in a human subject comprising administering autologous or allogeneic mesenchymal stem cells to the subject within six months of new onset type 1 diabetes (T1D) diagnosis.
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3. A method of treating new onset type 1 diabetes (T1D) in a human subject determined to be at high risk for the disease comprising administering autologous or allogeneic mesenchymal stem cells to the subject.
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53-74. -74. (canceled)
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