POROUS COATING INCORPORATING FLUID RESERVOIRS
First Claim
1. Porous coating for the controlled release of fluids such as drugs comprising a porous structure with internal reservoirs and passages, said reservoirs communicating with the external environment through said passages, in such a way that a fluid can move between the reservoirs and the external environment, characterized by the fact that for at least a group of said passages, each passage contains a restricting element which partially reduces the passage cross section and thereby induces a flow restriction for a fluid circulating through said passage.
1 Assignment
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Accused Products
Abstract
Porous coating for the controlled release of fluids such as drugs comprising a porous structure with internal reservoirs and passages, said reservoirs communicating with the external environment through said passages, in such a way that a fluid can move between the reservoirs and the external environment, characterized by the fact that for at least a group of said passages, each passage contains a restricting element which partially restricts the passage cross section.
24 Citations
27 Claims
- 1. Porous coating for the controlled release of fluids such as drugs comprising a porous structure with internal reservoirs and passages, said reservoirs communicating with the external environment through said passages, in such a way that a fluid can move between the reservoirs and the external environment, characterized by the fact that for at least a group of said passages, each passage contains a restricting element which partially reduces the passage cross section and thereby induces a flow restriction for a fluid circulating through said passage.
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26. Process for manufacturing a porous coating comprising the following steps:
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Providing an internal layer having a first porosity on a substrate, Providing an external layer having a second porosity on said internal layer, the pores diameter of the external layer being smaller than the pores diameter of the internal layer, Filling with a drug the pores of the internal layer, said filling being made through the pores of the external layer, characterized by the fact that the internal layer is positively charged, alternately negatively charged, the external layer is neutral and wherein the drug is negatively charged, alternately positively charged.
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27. Porous coating wherein the internal structure is positively charged, alternately negatively charged, the external structure in neutral, and wherein the drug is negatively charged, alternately positively charged.
Specification