×

ANALYSIS OF HETEROGENEOUS NUCLEIC ACID SAMPLES

  • US 20090325153A1
  • Filed: 04/21/2006
  • Published: 12/31/2009
  • Est. Priority Date: 04/21/2005
  • Status: Active Grant
First Claim
Patent Images

1. A method of detecting an altered or mutant nucleic acid molecule that is present at low frequency in a biological sample comprisingisolating a threshold number of genome equivalents of a target nucleic acid of low genomic complexity from a biological sample;

  • andanalyzing a statistically significant number of molecules of the isolated target nucleic acid using a technique useful for analyzing nucleic acid samples of high genomic complexity,wherein the analyzing provides information about the presence or absence of an altered or mutant nucleic acid molecule in the biological sample.

View all claims
  • 3 Assignments
Timeline View
Assignment View
    ×
    ×