FLUID HANDLING CASSETTE HAVING A SPECTROSCOPIC SAMPLE CELL
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Accused Products
Abstract
A fluid handling module is configured for removable engagement with a reusable main fluid handling instrument. The module includes a module housing and a first fluid passageway extending from the module housing. The first fluid passageway has a patient end remote from the housing. The first fluid passageway is configured to provide fluid communication with a bodily fluid in a patient. A fluid component separator is in fluid communication with the first fluid passageway. The fluid component separator is configured to separate at least one component from a portion of the bodily fluid drawn from the patient. A spectroscopic sample cell is configured to hold at least a portion of the first component.
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Citations
49 Claims
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1-27. -27. (canceled)
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28. A method of obtaining blood analyte concentration data from analysis of blood plasma, the method comprising:
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withdrawing whole blood from a patient'"'"'s vasculature through a fluid passageway; dividing a sample portion from the withdrawn whole blood; using at least one pump to direct the sample portion toward a fluid handling element, which comprises; a fluid component separator; a sample element having a sample measurement location coinciding with an analysis region of an analysis system; and a fluid interface; filling the sample element with the sample. portion of the withdrawn blood through the fluid interface; removing non-plasma from the plasma in the sample portion; positioning at least a portion of the remaining plasma at the sample measurement location; aligning the sample measurement location with the analysis region of the analysis system; preventing the plasma portion from moving while using the analyte detector to analyze the remaining plasma while the sample measurement location is aligned with the analysis region of the analysis system; and after analysis, displacing the sample portion from the sample element by filling the sample element with a flush fluid through the fluid interface, thereby preparing the sample element to analyze a subsequent sample portion. - View Dependent Claims (29, 30, 31, 32, 33, 34, 35, 36)
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37. A system for analyzing non-flowing blood plasma, the system comprising:
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an analysis system configured to determine the concentration of an analyte in plasma; a fluid controller configured to; withdraw blood from a patient; divide a sample portion from said withdrawn blood; and direct the sample portion toward a fluid handling element; the fluid handling element comprising a fluid interface and a sample element having a sample measurement location coinciding with an analysis region of the analysis system, the fluid handling element configured to prepare the sample portion for analysis by; removing non-plasma from plasma in the sample portion; positioning at least a portion of the remaining plasma at the sample measurement location; aligning the sample measurement location with the analysis region of the analysis system; and holding at least the plasma in a non-flowing state while the plasma at the sample measurement location is analyzed by the analysis system; wherein said fluid controller is further configured to transfer the sample portion through the fluid interface into the sample element and, after analysis, allow the flow of a flush fluid into the sample element through the fluid interface to prepare the fluid handling element to analyze a subsequent sample portion. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
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Specification