RESULT VALIDATION IN NON-INVASIVE CEREBRAL OXYGENATION LEVEL MONITORING
First Claim
1. A method for near-infrared (NIR) cerebral oxygenation level monitoring, comprising:
- causing an NIR optical source to introduce NIR optical radiation into the cerebral tissue of a patient for migration toward an NIR optical detector;
receiving a first signal representative of the NIR optical radiation detected by the NIR optical detector;
processing the first signal to produce a cerebral oxygenation level metric and outputting the cerebral oxygenation level metric on a user display;
processing the first signal to generate a second signal therefrom known to exhibit measurably significant timewise fluctuations corresponding to at least one intrinsic physiological oscillation in the patient when said NIR optical source and said NIR optical detector are in proper optical coupling with said cerebral tissue;
detecting whether said measurably significant timewise fluctuations are present in said second signal; and
outputting an indication of an error condition noticeable to a viewer of the user display if said measurably significant timewise fluctuations are not present in said second signal.
1 Assignment
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Accused Products
Abstract
Methods, systems, and related computer program products for optically monitoring a chromophore level in a body part of a patient are described. An optical source introduces optical radiation into the body part, and an optical detector receives optical radiation that has propagated through at least a portion of the body part and produces a first signal representative of the received optical radiation. The first signal is processed to produce a chromophore level metric, which is output on a user display, and is further processed to produce a second signal known to exhibit measurably significant timewise fluctuations corresponding to at least one intrinsic physiological oscillation of the patient when the optical source and the optical detector are in proper optical coupling with the body part. An error condition indication is provided if the measurably significant timewise fluctuations are not present in the second signal.
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Citations
20 Claims
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1. A method for near-infrared (NIR) cerebral oxygenation level monitoring, comprising:
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causing an NIR optical source to introduce NIR optical radiation into the cerebral tissue of a patient for migration toward an NIR optical detector; receiving a first signal representative of the NIR optical radiation detected by the NIR optical detector; processing the first signal to produce a cerebral oxygenation level metric and outputting the cerebral oxygenation level metric on a user display; processing the first signal to generate a second signal therefrom known to exhibit measurably significant timewise fluctuations corresponding to at least one intrinsic physiological oscillation in the patient when said NIR optical source and said NIR optical detector are in proper optical coupling with said cerebral tissue; detecting whether said measurably significant timewise fluctuations are present in said second signal; and outputting an indication of an error condition noticeable to a viewer of the user display if said measurably significant timewise fluctuations are not present in said second signal. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A system for near-infrared (NIR) cerebral oxygenation level monitoring, comprising:
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an NIR optical source for introducing NIR optical radiation into the cerebral tissue of a patient; an NIR optical detector for receiving NIR optical radiation that has migrated through at least a portion of the cerebral tissue, said NIR optical detector generating a first signal representative of the received NIR optical radiation; a first processor configured and adapted to process the first signal to generate a cerebral oxygenation level metric therefrom, said first processor being further configured and adapted to generate a second signal from the first signal, the second signal being known to exhibit measurably significant timewise fluctuations corresponding to at least one intrinsic physiological oscillation of the patient when said NIR optical source and said NIR optical detector are in proper optical coupling with the cerebral tissue; a user display for displaying the cerebral oxygenation level metric; and a second processor configured and adapted to detect whether the measurably significant timewise fluctuations are present in the second signal and to cause an indication of an error condition noticeable to a viewer of the user display if said measurably significant timewise fluctuations are not present in said second signal. - View Dependent Claims (13, 14, 15, 16)
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17. A computer program product stored on a computer-readable medium for facilitating patient monitoring, comprising:
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computer code for receiving a first signal representative of near-infrared (NIR) optical radiation that has been introduced into the cerebral tissue of a patient by an NIR optical source and that has been detected by an NIR optical detector after migrating through at least a portion of the cerebral tissue theretoward; computer code for processing the first signal to produce a cerebral oxygenation level metric for output onto a user display; computer code for processing the first signal to generate a second signal therefrom known to exhibit measurably significant timewise fluctuations corresponding to at least one intrinsic physiological oscillation in the patient when the NIR optical source and the NIR optical detector are in proper optical coupling with the cerebral tissue; computer code for detecting whether the measurably significant timewise fluctuations are present in the second signal; and computer code for outputting an indication of an error condition onto the user display if said measurably significant timewise fluctuations are not present in said second signal. - View Dependent Claims (18, 19, 20)
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Specification