OCULAR IMPLANT

• US 20090326432A1
• Filed: 01/25/2008
• Published: 12/31/2009
• Est. Priority Date: 01/25/2007
• Status: Active Grant

• Current Assignee: Universitaet Rostock
• Original Assignee: Universitaet Rostock
• Inventors: Schmitz, Klaus-Peter, Behrend, Detlef, Sternberg, Katrin, Schmidt, Wolfram, Guthoff, Rudolf
• Granted Patent: US 8,206,333 B2
• Time in Patent Office: Days
• US Class Current: 604/9
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

The present invention relates to an ocular implant, particularly a glaucoma stent.

It is the object of the present invention to devise an ocular implant which allows the ocular eye pressure to be regulated, i.e., to be maintained at a desired level, while preventing the flow resistance from increasing over time, for example due to fibrosis.

In order to achieve this object, the ocular implant according to the invention comprises a small tube (5), the wall surface (3) of which encloses a hollow duct that is open on both sides in the longitudinal direction of the hollow duct, wherein a first opening (1) allowing ocular humor to flow in and a second opening (2) allowing the ocular humor to be discharged is provided, and wherein the wall surface (3) is formed by a liquid-tight material, and wherein at least one pressure-controlled valve (4) is disposed in the area of the wall surface (3).

Claims

1. An ocular implant, comprising:

a small tube, the wall surface of which encloses a hollow duct that is open on both sides in the longitudinal direction of the hollow duct wherein a first opening allowing ocular humor to flow in and a second opening allowing the ocular humor to be discharged is provided, and wherein the wall surface is formed by a liquid-tight material,

wherein 35% of the longitudinal extent of the small tube from the first opening is positioned in the anterior eye chamber and

wherein at least one pressure-controlled valve is disposed in the area of the wall surface, which is disposed at distance from the first opening equal to between 0% and 35% of the longitudinal extent of the small tube.

2. The ocular implant according to claim 1, wherein the wall material and the wall thickness of the small tube are selected such that the small tube, after being inserted into the anterior chamber of the eye, remains placed therein in such a way that the second opening is positioned in the subconjunctival space or in the uveoscleral space.

3. The ocular implant according to claim 1, wherein the internal hollow duct of the small tube has a diameter of between 50 μ

m and 1000 μ

m.

6. The ocular implant according to claim 1, characterized in that wherein the small tube has a length of between 3 mm and 20 mm.

15. The ocular implant according to claim 1, wherein the wall surface of the small tube is formed of a flexible material, a metal or a metal alloy.

19. The ocular implant according to claim 1, wherein the valve is formed as a diaphragm valve or, as a tongue diaphragm valve.

20. The ocular implant according to claim 19, wherein the diaphragm valve is formed by a base and a circumferential separation of the wall surface or the tongue diaphragm valve is formed by a base and a tongue-shaped circumferential separation of the wall surface, wherein the wall surface is not separated in the area of the base.

22. The ocular implant according to claim 20, wherein the wall thickness of the wall surface is smaller in the area of the base than the wall thickness of the wall surface in the adjacent area outside the valve.

23. The ocular implant according to claim 22, wherein the wall thickness of the wall surface in the area of the base is between 30% and 80% of the wall thickness of the wall surface in the adjacent area outside the valve.

24. The ocular implant according to claim 20, wherein the base of the valve is directed to the first opening and the circumferential separation or the tongue-shaped circumferential separation is directed from the base in the direction of the second opening.

25. The ocular implant according to claim 1, wherein the valve has an area corresponding to between 5% and 10% of the area of the wall surface of the small tube.

26. The ocular implant according to claim 1, wherein the valve has a longitudinal axis extent along the longitudinal axis of the small tube that does not exceed 15% of the length of the small tube and a radial transverse extent that does not exceed 15% of the circumference of the small tube.

27. The ocular implant according to claim 1, wherein a plurality of valves (4) is provided.

29. The ocular implant according to claim 27, wherein a maximum of 4 valves (4) are disposed adjacently in the radial direction, and a maximum of 2 valves (4) are disposed one behind the other in the axial direction.

33. The ocular implant according to claim 26, wherein the valves is disposed at a distance from the first opening equal to between 5% and 35% of the longitudinal extent of the small tube.

34. The ocular implant according to claim 1, wherein the hollow duct comprises a flow limiter formed by an orifice, wherein the orifice comprises an opening the area of which is between 1000 and 3000 μ

m².

36. The ocular implant according to claim 34, wherein the orifice is disposed at a distance from the first opening corresponding to between 0% and 10% of the longitudinal extent of the small tube.

40. The ocular implant according to claim 1, wherein the at least one pressure-controlled valve is formed such that it opens continuously at a pressure of between 10 mm and 20 mm mercury column.

42. The ocular implant according to claim 20, wherein the diaphragm of the diaphragm valve or the diaphragm of the tongue diaphragm valve comprises at least one opening.

43. The ocular implant according to claim 42, wherein the at least one opening has an area of between 80 and 200 μ

m².

4-5. -5. (canceled)

7-14. -14. (canceled)

16-18. -18. (canceled)

21. (canceled)

28. (canceled)

30-32. -32. (canceled)

35. (canceled)

37-39. -39. (canceled)

41. (canceled)