Antimicrobial Topical and Other Preparations Containing Fluorescent or Illumination Dye and Tracer Agents or Compounds

• US 20100003198A1
• Filed: 07/06/2009
• Published: 01/07/2010
• Est. Priority Date: 07/07/2008
• Status: Abandoned Application

• Current Assignee: Jonathan P. Stolmeier, Patrick John Stolmeier
• Original Assignee: Jonathan P. Stolmeier, Patrick John Stolmeier
• Inventors: Stolmeier, Jonathan P., Stolmeier, Patrick John
• Application Number:
  US12/498,217
• Publication Number:
  US 20100003198A1
• Time in Patent Office: Days
• US Class Current: 424/10.3
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/045 Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
• CPC Class Codes: A61K 31/09 having two or more such linkages
• CPC Class Codes: A61K 31/155 Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

A formulation for topical application to human skin and other surface preparation compositions containing antimicrobial, antifungal and antiviral compounds which remain on human skin and other surface compositions to reduce or dominate bacteria, virus and fungi present, prevent future contamination by their presence and substantive character, contain agents or compounds that contain antibacterial, antiviral and antifungal properties and flourescent dyes and tracers that contain illumination properties exhibiting various colons including clear and no color pigment, that when exposed to certain light such as ultraviolet, will produce an illumination effect in various colors including dear and no color for a period of time within a preferred range of thirty minutes to six hours or longer from the time of initial application, and prior to for instance application of ultraviolet light, such flourescent dyes and tracers appear to be clear in color, invisible or have no color pigment showing on the skin or other surfaces, but when exposed to for instance ultraviolet fight, the surface illuminates allowing a person to determine if human skin or other surface has been adequately covered with the antibacterial, antifungal or antiviral composition agent or compound, and to significantly increase the activity to reduce and eliminate bacteria, virus and fungi on the surface, and support programs for antibacterial, antifungal and antiviral quality control, compliance, verification and education for industry and human handwash technique.

Claims

1. An illumination or tracer formulation, wherein said illumination or tracer agent or compound is an antibacterial, antifungal or antiviral topical human skin or other surface formulation comprising of an antimicrobial agent selected from a group of chloroxylenol, chlorhexidine, alcohol, iodine, triclosan and their derivatives, metal alloys or ions to include copper, zinc and silver and their derivatives, other antimicrobial compounds and their derivatives known in poor art and agents or compounds known in prior art as compatible with use of antimicrobial topical human skin or other surface agents or compounds wherein such agents or compounds are included with flourescent dye or tracer agents or compounds with illumination properties known in prior art when exposed to light such as ultraviolet, the solution will produce an illumination effect, otherwise, the dye will appear to have no color properties and invisible.

2. An illumination or tracer formulation according to claim 1, wherein said illumination or tracer agent or compound is 005 to 5.0% of an illumination flourescent or tracer agent or compound, wherein the illumination or tracer agent or compound is selected from a group of Federal Department of Agriculture, Environment Protection Agency or Federal Drug Administration approved dyes with illumination or tracer properties such as FD&

C flourescent Dye (DNC) (MX659 Pylam-Cert Fluorescent or Distyrl Bipheryl), and Synthetic Organic Colorant of various colors, textures and consistencies, in the form of a powder, liquid or gel.

3. An illumination or tracer formulation according to claim 1, wherein said illumination or tracer agent or compound is the illumination flourescent or tracer agent or compound particles or molecules that are of different size wherein the longevity or duration of the illumination or tracer effect can be regulated and measured from 30 minutes to six hours, or longer.

4. An illumination or tracer formulation according to claim 1, wherein said illumination or tracer agent or compound is 0.005 to 5.0% of an illumination flourescent or tracer agent or compound, wherein the illumination or tracer agent or compound has an anti-microbial effect.

5. An illumination or tracer formulation according to claim 1, wherein said illumination or tracer agent or compound is the illumination flourescent or tracer agent or compound, when applied to a surface such as human skin or other surface such as metal, plastic, rubber, fabric, nylon, wood, leather, vinyl, ceramics, composites, derivatives or combinations thereof and other surfaces known in prior art, appear to have no visible color, color pigment, illumination or tracer properties.

6. An illumination or tracer formulation according to claim 1, wherein said illumination or tracer compound is the illumination flourescent or tracer agent or compound, when applied to a surface such as human skin, or other surface such as metal, plastic, rubber, fabric, nylon, wood, leather, vinyl, ceramics, composites, derivatives or combinations thereof and other surfaces, known in prior art, appear to have no visible color, color pigment, illumination or tracer properties until exposed to light, such as ultra violet, the illumination flourescent or tracer properties are activated and visible in a color such as green, blue, yellow, orange, white or clear.

7. An illumination or tracer formulation according to claim 1, wherein said illumination or tracer agent or compound is a flourescent or illumination tracer agent or compound wherein the longevity or duration of the illumination period may be regulated from thirty minutes to six hours or more by adding various chemicals, agents or compounds into for instance a micro-capsule, and for such micro-capsule to erode, dissolve or rupture and release its contents by effect such as friction, time release, temperature, and mix with an illumination flourescent or a tracer agent or compound.

8. The formulation according to claim 1, wherein the active ingredient is an antibacterial, antifungal or antiviral agent or compound.

9. The formulation according to claim 1, wherein an anchoring agent or compound consists of various percentages of an agent or compound such as selected from a group of diisopropyl adipate, diisobutyl adipate, higher fatty acid ployoxethylene glycerol and polyglycerol or essential oils.

10. The formulation according to claim 1, wherein the antibacterial agent or compound is chloroxylenol or a chloroxylenol derivative.

11. The formulation according to claim 1, wherein a polyol is selected from a group consisting of propylene glycol or a glycol derivative.

12. The formulation according to claim 1, wherein the antibacterial, antifungal or antiviral agent or compound is selected from the group consisting of chlorhexidine or its derivatives, such as chlorhexidine gluconate, chlorhexidine digluconate, chlorhexidine diacetate, chlorhexidine dihydrochloride, or it may be selected from the group consisting of nisin, bis-diguanides, polyhexamethylene biguanide (PHMB), benzalkonium chloride (BAC), benzethonium chloride (BZC), methylbenzethonium chloride, triclosan, triclocarban, tribromsalan, amyltricresols, parachlorometaxylenol (PCMX), phenol, iodine, nonylphenoxypoly (ethyleneoxy) ethanoliodine, poloxamer-iodine complex, undecoylium chloride iodine complex, bisquaternary ammnium compounds, plymeric quaternary ammonium compounds, alcohols, cationic peptides, organometaulic antiseptics, alkyl pyridinium salts such as cetyl pyridinium chloride (CPC), metal alloys such as silver, copper or zinc, their ions and combinations and derivatives generated electrolytically or non electrolytically, in particle, flake or powder form, essential oils, and their combinations and derivatives;

and wherein the anchoring agent is selected from the group consisting of propylene glycol or glycol derivative.

13. The formulation according to claim 1, wherein the anchoring agent or compound consisting of propylene glycol or glycol derivative is 0.25 to 5.0%.

14. The formulation according to claim 1, further comprising an agent or compound selected from a group consisting of deionized water, ethyl alcohol, isopropyl alcohol, geraniol, inalool, thujanoi, myrcenol, terpineol, menthol, piperitol, alcohol derivatives, citric acid or its derivatives, triethanolamine, polyacrylic acid, various fragrances, ethylenediamine tetra acid or octylphenol ethoxalate.

15. The formulation according to claim 1, wherein agents or compounds, and material known in prior art that are compatible with use of antibacterial, antiviral and antifungal agents and compounds known in the prior art selected from a group of wax, paint, epoxy, lacquer, polyurethane, varnish, plastic and polymers.

16. A formulation according to claim 1, wherein the antibacterial, antifungal and antiviral agent or compound is selected from a group of therapeutic, non therapeutic or synthetic essential oils and their derivatives, organic agents and their derivatives, such as tea tree, lavender, thyme, thymol, carvacrol, eugenol, cinnamic, lemon grass, lemon oil, oregano, citrus, bergamot, orange, clove, anise, cinnamon, eucalyptus, spruce, grapefruit pine, cineole, moroterpenol, liralool oxide, rare crypton, aldehydes and dlimonene.

17. A formulation of reducing or eliminating the number of micro-organisms on the surface of human skin, hair, nails and other surfaces such as metal, metal alloys, plastic, rubber, ceramics, fabrics, nylon, wood, leather, composites thereof and other surfaces known in prior art. Said formulation comprising of a topical human skin and other surface sanitizing and cleansing solution, liquid, lotion, wash, soap, antiseptic, disinfectant, applied to human skin or other surface, to a towelette or surface liquid cleanser and disinfectant comprised of an aqueous solution of water-soluble or nonwater-soluble organic or inorganic agents or compounds in an amount effective to eliminate or inhibit the growth of nitro-organisms, comprised of an illumination flourescent dye or tracer agent or compound of various colors including clear and no color pigment, capable of producing antimicrobial activity and an illumination effect on human skin and other surface that once exposed to light, such as ultraviolet will cause an illumination of the surface, otherwise the illumination compound appears invisible, and having referred formulations of:

a. Deionized Water 70-85%

Ethyl Alcohol 0.1-90.0%

Propylene Glycol 0.25-5.0%

Triethanolamine 0.59%

Polyacrylic Acid 0.43%

Chloroxylenol 0.1-5.0%

FD&

C Fluorescent Dye (DNC) or a Synthetic

Organic Colorant 0.005-5.0%

(MX659 Pylam-Cert Flourescent) (Day-Glo DG-00, A-594-5)

Fragrance 0.20%

b. Deionized Water 70-85%

Isopropyl Alcohol 0.1-90.0%

Propylene Glycol 0.25-5.0%

Triethanolamine 0.59%

Polyacrylic Acid 0.43%

Chloroxylenol 0.1-5.0%

FD&

C Flourescent Dye (DNC) or a Synthetic

Organic Colorant 0.005-5.0%

(MX659 Pylam-cert Flourescent) (Day-Glo DG-00, A-594-A)

Fragrance 0.20%

c. Deionized Water 80-99%

Isopropyl Alcohol 0.1-90.0%

Distyrl Biphenyl (Tenapol) 0.005-5.0%

Ethylenediamine Tetra Acitic Acid (EDTA) 0.14-5.4%

Propylene Glycol 0.25-5.0%

Octylphenol Ethoxalate 2.00%

Chloroxylenol 0.1-5.0%

Fragrance 0.20%

d. Deionized Water 80-99%

Ethyl Alcohol 0.1-90.0%

Distyrl Biphenyl (Tenapol) 0.005-5.0%

Ethylenediamine Tetra Acitic Acid (EDTA) 0.14-5.4%

Propylene Glycol 0.25-5.0%

Octylphenol Ethoxalate 2.00%

Chloroxylenol 0.1-5.0%

Fragrance 0.20%

e. Deionized Water 80-99%

Isopropyl Alcohol 0.1-90.0%

FD&

C Fluorescent Dye (DNC) or Synthetic

Organic Colorant 0.005-5.0%

Ethylenediamine Tetra Acitic Acid (EDTA) 0.14-5.4%

Propylene Glycol 0.25-5.0%

Octylphenol Ethoxalate 2.00%

Chloroxylenol 0.1-5.0%

Fragrance 0.20%

f. Deionized Water 80-99%

Ethyl Alcohol 0.1-90.0%

FD&

C Fluorescent Dye (DNC) or Synthetic

Organic Colorant 0.005-5.0%

Ethylenediamine Tetra Acitic Acid (EDTA) 0.14-5.4%

Propylene Glycol 0.25-5.0%

Octylphenol Ethoxalate 2.00%

Chloroxylenol 0.1-5.0%

Fragrance 0.20%

18. Formulations contained in a thru f above may include one or more of the following agents or compounds, derivatives of each, combinations, and in various amounts.

a. Deionized Water

Glycerin

Glyceryl Stearate PEG-100 Stearate

Isopropyl Mysistate (IPM)

Chlorhexidine

Triclosan

Iodine

Cetylpyridinium chloride

Xylitol

Copper

Zinc

Silver

Electrolytically or non electrolytically generated copper, silver and zinc ions Synthetic Organic Colorant of various colors, textures, particles and forms (liquid, gel and powder)

Essential oils of various types, odors, mixtures, therapeutic or non therapeutic or synthetic essential oils and their derivatives, organic agents and their derivatives such as tea tree, lavender, thyme, thymol, carvacrol, eugenol, cinnamic, lemon grass, lemon oil oregano, citrus, bergamot, orange, clove, anise, cinnamon, eucalyptus, spruce, grapefruit, pine, cineole, moroterpenol, liralool oxide, rare crypton, aldehydes and dlimonene, wintergreen, spearmint, along with sorbitol, polysorbates, propylene glycol, tochopherol, various alcohols and sodium chloride.

19. A formulation for a human skin sanitizing and cleansing solution, lotion, wash, shampoo and other surface liquid cleanser and disinfectant comprised of an aqueous solution of water-soluble or nonwater-soluble organic or inorganic agents or compounds in an amount effective to eliminate or inhibit the growth of micro-organisms, comprised of an illumination flourescent dye or tracer agent or compound of various colors including clear and no color pigment, capable of producing antimicrobial activity and an illumination effect upon human skin and other surface, when exposed to light such as ultraviolet, wherein the illumination upon human skin or other surface will dissipate and cease to illuminate within a preferred range of thirty-minutes to six hours or more from the time of initial application, and prior to for instance application of ultraviolet light, such flourescent dyes and tracers appear to be clear or invisible or have no color pigment showing on human skin or other surface, but when expose to for instance ultraviolet light, the surface becomes illuminated.

20. A formulation to control, set or stage the time period for when the illumination producing dyes or tracers cease to produce their illumination properties by for instance adding various formulations of chemicals, agents or compounds that when exposed to various illumination producing dyes or tracers they terminate in whole or in part, the illumination producing properties of such dyes or tracers on human skin and other surfaces. Such chemicals, agents or compounds may be combined into a micro-capsule, and adding that micro-capsule into the formulations referred herein, and for such micro-capsule to erode, dissolve, rupture or release its contents into the formulations by such effect such as friction, various periods of time, various temperature or environmental condition or effect known in prior art, as time release or micro encapsulation processes.