Identifying White Matter Fiber Tracts Using Magnetic Resonance Imaging (MRI)
First Claim
1. A method for magnetic resonance imaging comprising:
- obtaining a fiber tract atlas for a nervous system, the fiber tract atlas comprising;
a plurality of atlas voxels that each represent a different volume element of the nervous system, the plurality of atlas voxels including a first atlas voxel that represents a first volume element of the nervous system, andinformation on orientations of a first fiber tract in the first volume element of the nervous system;
acquiring magnetic resonance data from the nervous system of a subject, the magnetic resonance data comprising a plurality of data voxels including a first data voxel that relates to the first atlas voxel;
generating a diffusion vector for the first data voxel based at least in part on the acquired magnetic resonance data; and
using the fiber tract atlas to find a probability that the first data voxel represents the first fiber tract, based at least in part on the generated diffusion vector and the information on the orientations of the first fiber tract in the first volume element.
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Abstract
Systems, methods, and software are used for identifying fibers based at least in part on magnetic resonance imaging. A fiber tract atlas for a nervous system includes atlas voxels that each represent a different volume element of the nervous system; a first atlas voxel represents a first volume element of the nervous system. The fiber tract atlas also includes information on orientations of a first fiber tract in the first volume element of the nervous system. Magnetic resonance data is acquired from the nervous system of a subject. The magnetic resonance data includes data voxels; a first data voxel relates to the first atlas voxel. A diffusion vector is generated for the first data voxel based at least in part on the acquired magnetic resonance data. The fiber tract atlas is used to find a probability that the first data voxel represents the first fiber tract based at least in part on the generated diffusion vector and the information on the orientations of the first fiber tract in the first volume element.
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Citations
22 Claims
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1. A method for magnetic resonance imaging comprising:
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obtaining a fiber tract atlas for a nervous system, the fiber tract atlas comprising; a plurality of atlas voxels that each represent a different volume element of the nervous system, the plurality of atlas voxels including a first atlas voxel that represents a first volume element of the nervous system, and information on orientations of a first fiber tract in the first volume element of the nervous system; acquiring magnetic resonance data from the nervous system of a subject, the magnetic resonance data comprising a plurality of data voxels including a first data voxel that relates to the first atlas voxel; generating a diffusion vector for the first data voxel based at least in part on the acquired magnetic resonance data; and using the fiber tract atlas to find a probability that the first data voxel represents the first fiber tract, based at least in part on the generated diffusion vector and the information on the orientations of the first fiber tract in the first volume element. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A magnetic resonance imaging (MRI) system comprising:
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a magnetic resonance data acquisition system adapted to acquire magnetic resonance data from a nervous system of a subject, the magnetic resonance data comprising a plurality of data voxels including a first data voxel; and a data processor that receives the magnetic resonance data from the magnetic resonance data acquisition system and comprises; a mechanism that obtains a fiber tract atlas for the nervous system from the magnetic resonance data, the fiber tract atlas comprising; a plurality of atlas voxels that each represent a different volume element of the nervous system, the plurality of atlas voxels including a first atlas voxel that represents a first volume element of the nervous system, the first data voxel relating to the first atlas voxel; and information on orientations of a first fiber tract in the first volume element of the nervous system; a mechanism that generates a diffusion vector for the first data voxel based at least in part on the acquired magnetic resonance data; and a mechanism that processes the fiber tract atlas to find a probability that the first data voxel represents the first fiber tract, based at least in part on the generated diffusion vector and the information on the orientations of the first fiber tract in the first volume element. - View Dependent Claims (13, 14, 15, 16)
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17. An article comprising a machine-readable medium storing instructions adapted to cause data processing apparatus to perform operations comprising:
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obtaining a fiber tract atlas for a nervous system, the fiber tract atlas comprising; a plurality of atlas voxels that each represent a different volume element of the nervous system, the plurality of atlas voxels including a first atlas voxel that represents a first volume element of the nervous system, and information on orientations of a first fiber tract in the first volume element of the nervous system; acquiring magnetic resonance data from the nervous system of a subject, the magnetic resonance data comprising a plurality of data voxels including a first data voxel, the first data voxel relating to the first atlas voxel; generating a diffusion vector for the first data voxel based at least in part on the acquired magnetic resonance data; and using the fiber tract atlas to find a probability that the first data voxel represents the first fiber tract, based at least in part on the generated diffusion vector and the information on the orientations of the first fiber tract in the first volume element. - View Dependent Claims (18, 19, 20, 21, 22)
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Specification