Cartridge And Medical Delivery System Accommodating Such Cartridge

• US 20100004603A1
• Filed: 09/02/2009
• Published: 01/07/2010
• Est. Priority Date: 08/27/2001
• Status: Active Grant

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: NIELSEN, Lars Korsbjerg, JENSEN, Morten Baek, STEENGAARD, Kim, KRISTENSEN, Lars Thougaard
• Granted Patent: US 8,177,767 B2
• Time in Patent Office: Days
• US Class Current: 604/207
• CPC Class Codes: A61J 2205/40 by shape or form, e.g. by using shape recognition
• CPC Class Codes: A61M 2205/6045 having complementary physical shapes for indexing or registration purposes
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06

Abstract

A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitted in to a circular contour in the housing. The outer diameter of the protrusion on the distal end of the cartridge is chosen as a larger diameter for a higher concentration of insulin. In this way only a cartridge containing the correct concentration or a lower concentration fits into a delivery system designed for a specific concentration of insulin.

Claims

1. A medication delivery system for delivering medication from a cartridge, the medication delivery system comprising:

a medication delivery device that is calibrated and designed for a specific concentration of a medication and wherein the medication delivery device has a cartridge receiving portion with a shape and diameter so that the medication delivery device accepts only cartridges that use a specific mechanical coding that corresponds to the concentration for which the device is designed and calibrated, or a lower concentration;

a cartridge containing one of a plurality of different concentrations of medication, the cartridge containing at least one mechanical coding selected from a plurality of mechanical codings, the mechanical coding(s) comprising at least one circular element(s) shaped as substantially continuous circumferential protrusion having a circular cross section when viewed in an axial cross section of the cartridge and extending radially outward from a cylindrical portion of the cartridge and having a diameter with a predetermined value and a predetermined shape that allows it to fit into the cartridge receiving portion of the medication delivery device and wherein the cartridge is structured to be axially insertble into a medical delivery device in any rotational orientation; and

wherein the selected mechanical coding(s) allow(s) the cartridge to be used only in a delivery device designed and calibrated for the concentration indicated by the selected mechanical coding(s), or a lower concentration, wherein the mechanical coding(s) comprise protrusion(s) having different diameter(s) and/or different length L from a distal surface.

2. The medication delivery system of claim 1, wherein the medication is insulin and the medication delivery system is an injection device and wherein at least one of the mechanical codings is indicative of 100 IU per ml insulin and wherein the medication delivery device is designed and calibrated for 100 IU per ml medications and wherein the cartridge receiving portion of the medication delivery device accepts cartridges having the mechanical coding thereby allowing only specific cartridges containing 100 IU per ml concentrations to be inserted and used with the medication delivery system.

3. The medication delivery system of claim 2 wherein at least one of the mechanical codings is indicative of an insulin having a concentration of something other than IU 100 insulin.

4. The medication delivery system of claim 1, wherein each diameter size corresponds to a specific concentration.

5. The medication delivery system of claim 1, wherein a larger diameter mechanical coding is indicative of a higher concentration of the medicament adapted to be stored in the cartridge.

6. A cartridge comprising:

a medication storing portion suitable for use in a medication delivery device, wherein the medication storing portion of the cartridge is adapted to store a medicament that is available in a plurality of concentrations;

at least one mechanical coding comprising at least one circular element(s) shaped as a substantially continuous circumferential protrusion(s) when viewed in an axial cross section of the cartridge, the circular element(s) having a diameter and extending radially outwards from a cylindrical portion of the cartridge and wherein at least the diameter of the circular element mechanical coding(s) are indicative of a specific concentration of the medicament and wherein the mechanical coding is structured to allow the cartridge to be used only in medication delivery devices that are configured to mechanically accept the circular element mechanical coding(s) and the cartridge.

7. A cartridge according to claim 6, wherein the outer surface is generally cylindrical and the selected mechanical coding comprises a protrusion having a specific diameter and shape that allows the cartridge to be inserted and used only in specific medication delivery devices that are designed and calibrated for 100 IU per ml concentrations.

8. A cartridge according to claim 7, wherein the medicament comprises an insulin.

9. A cartridge according to claim 6, wherein the medicament is an insulin and wherein.

10. A cartridge according to claim 9, wherein the mechanical coding is on an adapter that is disposed on an outer cylindrical wall of the cartridge wherein the adapter is in the form of a sleeve that jackets at least the medicaton storing portion of the cartridge and wherein the mechanical coding has a circular cross section.

11. A cartridge according to claim 6, wherein a larger diameter mechanical coding is indicative of a higher concentration of the medicament adapted to be stored in the medication storing portion.

12. A medication cartridge adapted for use with a medication delivery device, the cartridge comprising:

a body having a cylindrical wall around a medication storing compartment;

a medication selected from a group of medications suitable for delivery with the medication delivery device and stored in the medication storing compartment; and

a mechanical coding;

wherein the mechanical coding comprises at least one circular element(s) shaped as a substantially continuous protrusion having a circular cross section when viewed in an axial cross section of the cartridge and extending circumferentially and radially with respect to the cylindrical wall;

wherein the mechanical coding is indicative of the specific type of medication in the cartridge, and allows the cartridge to be used only in medications delivery devices that are configured to mechanically accept the mechanical coding and the cartridge.

13. The medication cartridge of claim 12, wherein the specific type of medication is a 100 IU per ml concentration of medication.

14. The medication cartridge of claim 12, wherein the mechanical coding is integral with the cylindrical wall of the cartridge.

15. The medication cartridge of claim 12, wherein the mechanical coding is located a distance L from a distal end of the cartridge so that the mechanical coding is located between a distal and a proximal end of the cartridge body and wherein the coding has a diameter D that is larger than the diameter of the cylindrical wall of the body.

16. The medication cartridge of claim 12, wherein the protrusion that forms the mechanical coding is located on an adapter sleeve that jackets the cylindrical wall.

17. The medication cartridge of claim 16, wherein the mechanical coding is structured to align the cartridge axially within a cartridge receiving portion of one or more of the medication delivery devices that have been determined in advance to be suitable for use with the medication in the cartridge.

18. The medication cartridge of claim 17, wherein the medication is an insulin and wherein the mechanical coding has a shape complimentary to the shape of the cartridge receiving portion.

19. The medication cartridge of claim 12, wherein a larger diameter mechanical coding is indicative of a higher concentration of the medicament adapted to be stored in the medication storing compartment.

20. A method of using a medication delivery system for delivering medication from a cartridge, the method comprising:

providing a medication delivery device that is calibrated and designed for a specific concentration of a medication and wherein the medication delivery device has a cartridge receiving portion with a shape and diameter so that the medication delivery device accepts only cartridges that use a specific mechanical coding that corresponds to the concentration for which the device is designed and calibrated, or a lower concentration;

providing a cartridge containing one of a plurality of different concentrations of medication, the cartridge containing at least one mechanical coding selected from a plurality of mechanical codings, the mechanical coding(s) comprising at least one circular element(s) shaped as substantially continuous circumferential protrusion having a circular cross section when viewed in an axial cross section of the cartridge and extending radially outward from a cylindrical portion of the cartridge and having a diameter with a predetermined value and a predetermined shape that allows it to fit into the cartridge receiving portion of the medication delivery device and wherein the cartridge is structured to be axially insertble into a medical delivery device in any rotational orientation; and

wherein the selected mechanical coding(s) allow(s) the cartridge to be used only in a delivery device designed and calibrated for the concentration indicated by the selected mechanical coding(s), or a lower concentration, wherein the mechanical coding(s) comprise protrusion(s) having different diameter(s) and/or different length L from a distal surface.