DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE
First Claim
1. An implantable electrolytic pump comprising:
- an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid;
a cannula for conducting liquid from the drug chamber; and
electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon.
1 Assignment
0 Petitions
Accused Products
Abstract
Embodiments of an implantable electrolytic pump include an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid. The pump further includes a cannula for conducting liquid from the drug chamber and electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon.
-
Citations
29 Claims
-
1. An implantable electrolytic pump comprising:
-
an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid; a cannula for conducting liquid from the drug chamber; and electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
-
-
11. An implantable osmotic pump comprising:
-
a drug chamber; an osmosis chamber having a first portion exposed to facilitate contact with a surrounding fluid; an expandable diaphragm separating the drug chamber and the osmosis chamber; and a cannula for conducting liquid from the drug chamber, wherein the osmosis chamber preferentially draws a surrounding fluid into the osmotic chamber, thereby driving the expandable diaphragm toward the drug chamber and forcing fluid from the drug chamber into the cannula. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18)
-
-
19. A method of administering a drug, the method comprising the steps of:
-
providing a pump comprising an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber being in contact with the drug chamber and with a surrounding fluid; and activating the electrolysis chamber to dispense a volume of drug from the drug chamber, whereby the drug chamber decreases in volume following drug dispensation, the osmosis chamber admitting water from the surrounding fluid to offset the decreased volume of the drug chamber and prevent buildup of vacuum pressure thereon. - View Dependent Claims (20, 21, 22, 23)
-
-
24. A method of administering a drug, the method comprising the steps of:
-
providing a pump comprising a drug chamber, an osmosis chamber having a first portion exposed to facilitate contact with a surrounding fluid, and an expandable diaphragm separating the drug chamber and the osmosis chamber; and exposing the first portion of the osmosis chamber to a fluid to preferentially draw the fluid into the osmotic chamber, thereby driving the expandable diaphragm toward the drug chamber and forcing fluid from the drug chamber into the cannula. - View Dependent Claims (25, 26, 27, 28, 29)
-
Specification