APPARATUS FOR INTRA-OCULAR INJECTION

• US 20100010452A1
• Filed: 01/09/2008
• Published: 01/14/2010
• Est. Priority Date: 01/09/2007
• Status: Active Grant

• Current Assignee: Fondation Ophtalmologique Adolphe De Rothschild, Fovea Pharmaceuticals SA (Sanofi )
• Original Assignee: Foudation Ophtalmologique Adolphe De Rothschild, Fovea Pharmaceuticals SA (Sanofi )
• Inventors: Paques, Michel, Roy, Pierre
• Granted Patent: US 9,308,125 B2
• Time in Patent Office: Days
• US Class Current: 604/192
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61M 5/3287 Accessories for bringing the needle into the body; Automatic needle insertion A61M5/20, A61M5/31525 take precedence
• CPC Class Codes: A61M 5/427 Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates

Abstract

The present technology relates to an apparatus for intraocular injection comprising a plate adapted for being brought into contact with an eye and a guide operable to guide a needle into the interior of an eye, characterized in that it comprises means for displacing a superficial layer (1) of the eye over an underlying layer (2) of the eye as the plate is brought into contact with the eye before the needle is guided into the interior of the eye.

Claims

1. An apparatus for intraocular injection comprising a plate adapted for being brought into contact with an eye, a guide operable to guide a needle into the interior of an eye, and a member operable to displace a superficial layer (1) of the eye over an underlying layer (2) of the eye as the plate is brought into contact with the eye before the needle is guided into the interior of the eye.

2. The apparatus according to claim 1, wherein the member operable to displace a superficial layer (1) over an underlying layer (2) is a resilient member which can be bent when urged against the superficial layer (1), whereby the resilient member applies a tangential force to the superficial layer (1).

3. The apparatus according to claim 2, wherein the resilient member comprises a flexible leg protruding from the plate.

4. The apparatus according to claim 2, wherein the member operable to displace a superficial layer (1) over an underlying layer (2) comprises means for engaging the superficial layer (1).

5. The apparatus according to claim 4, wherein the means for engaging the superficial layer comprises at least one tooth.

6. The apparatus according to claim 3, wherein the tooth is provided at a free end of the flexible leg.

7. The apparatus according to claim 1, wherein the plate comprises a cut-out having an edge adapted to be positioned along the limbus delimiting the cornea and the sclera of the eye, so as to adjust the position of the guiding means with respect to the limbus.

8. The apparatus according to claim 7, wherein the edge of the cut-out is of substantially circular shape.

9. The apparatus according to claim 7, wherein the edge of the cut-out has a shape which corresponds to a shape of a limbus so that the edge can be superimposed on the limbus.

10. The apparatus according to claim 9, wherein the cut-out is arranged in the plate such that when the edge of the cut-out is superposed on the limbus, the plate extends over the sclera of the eye.

11. The apparatus according to claim 7, wherein the cut-out and the guiding means guide are arranged so that the needle penetrate into the eye through the sclera at a distance of about 3.5 millimetres from the limbus.

12. The apparatus according to claim 1, wherein the plate has an eye bearing surface having a curved shape for matingly bearing on the outer surface of the eye.

13. The apparatus according to claim 1, wherein the guide comprises a support having a hollow body adapted for receiving a barrel of a syringe, such that the syringe can slide relative to the body.

14. The apparatus according to claim 13, wherein the syringe is movable relative to the body from a retracted position wherein a needle of the syringe is retracted inside the body, to an injection position wherein the needle protrudes outside the body.

15. The apparatus according to claim 14, comprising a syringe barrel and a syringe plunger, wherein operating a plunger of the syringe received inside the hollow body sequentially slides the syringe towards the injection position and then slides the plunger relative to the barrel.

16. The apparatus according to claim 14, wherein the support comprises a bearing surface against which a rim of the syringe can abut, so that operating a plunger of the syringe causes sequentially the syringe to slide relative to the body towards the injection position until the rim of the barrel abut against the bearing surface and then the plunger to slide into the syringe barrel.

17. The apparatus according to claim 14, comprising releasable connecting means for connecting a syringe plunger and a syringe barrel of the syringe in common sliding movement relative to the body and releasing said connection at a predetermined position of the syringe relative to the body.

18. The apparatus according to claim 17, wherein the releasable connecting means comprises at least one elastic member prestressed against an inner wall of the body, said inner wall having a housing for accommodating the elastic member when the syringe reaches the predetermined position so as to release the elastic member whereby the plunger is allowed to slide relative to the barrel.

19. The apparatus according to claim 18, wherein the releasable connecting means comprises a spacer arranged between the syringe barrel and the syringe plunger to prevent sliding movement of the plunger relative to the barrel.

20. The apparatus according to claim 18, wherein the spacer has grooves for receiving fingers of the plunger and the prestressed elastic member is adapted for preventing the fingers from sliding in the grooves until the elastic member is released.

21. The apparatus according to claim 14, comprising a push button for operating the plunger.

22. The apparatus according to claim 13, wherein the support comprises a finger bearing flange projecting outwardly from the body for an operator to retain the support when sliding the syringe relative to the body.

23. The apparatus according to claim 1, comprising a syringe barrel and a syringe needle, wherein the syringe barrel comprises a carpule sealed by a protective cap, the needle being movable rearwards relative to the carpule for simultaneously connecting the needle to the barrel to assemble the syringe and piercing the protective cap with the needle, before moving the assembled syringe towards an injection position.

24. The apparatus according to claim 23, comprising a needle support for supporting the syringe needle, the needle support being operable from outside the body for moving the needle relative to the carpule in order to pierce the protective cap.

25. The apparatus according to claim 23, comprising a removable safety ring for preventing movement of the needle relative to the body.

26. The apparatus according to claim 1, wherein the guide comprises a support having a hollow body, the hollow body comprising a fixed part and a mobile part which can slide relative to the fixed part, the mobile part being adapted for receiving a barrel of a syringe, such that the syringe and the mobile part can move in a common sliding movement relative to the fixed part.

27. The apparatus according to claim 26, comprising a locking member for preventing accidental movement of the mobile part relative to the fixed part.

28. The apparatus according to claim 27, wherein the locking member comprises a locking projection which can be accommodated in a locking recess, the apparatus comprising means for removing the locking projection from the locking recess, whereby allowing movement of the mobile part relative to the fixed part.

29. The apparatus according to claim 26, wherein the mobile part surrounds the fixed part.

30. The apparatus according to claim 26, comprising a rubbing member which generates friction between the fixed part and the mobile part thereby slowing down the movement of the mobile part relative to the fixed part.

31. The apparatus according to claim 26, comprising a resilient member arranged between a plunger of the syringe and the mobile part, the resilient member being adapted for exerting a restoring force which goes against a sliding movement of the plunger relative to the barrel of the syringe.

32. The apparatus according to claim 31, wherein operating the mobile part sequentially causes the mobile part to slide relative to the fixed part and then the plunger to slide relative to the barrel.

33. The apparatus according to claim 26, comprising a resilient member arranged between the fixed part and the mobile part, the resilient member being adapted for exerting a restoring force which goes against a sliding movement of the mobile part relative to the fixed part.

34. The apparatus according to claim 33, wherein operating a plunger of the syringe sequentially slides the mobile part relative to the fixed part until the restoring force reaches a predetermined limit and then slides the plunger relative to the barrel.

35. The apparatus according to claim 31, wherein the resilient member exerts a restoring force which causes the syringe to spontaneously retract into the hollow body after injection.