USE OF NATURAL, RECOMBINANT AND SYNTHETIC RESILINS IN COSMETICS

• US 20100015070A1
• Filed: 11/07/2007
• Published: 01/21/2010
• Est. Priority Date: 11/08/2006
• Status: Abandoned Application

• Current Assignee: BASF SE
• Original Assignee: BASF SE
• Inventors: Ptock, Arne, Raunft, Evelyn, Bollschweiler, Claus, Liebmann, Burghard, Fehr, Marcus, Hümmerich, Daniel
• Application Number:
  US12/513,709
• Publication Number:
  US 20100015070A1
• Time in Patent Office: Days
• US Class Current: 424/59
• CPC Class Codes: A61K 8/64 Proteins; Peptides; Derivatives or degradation products thereof
• CPC Class Codes: A61Q 1/02 Preparations containing skin colorants, e.g. pigments preparations in powder form A61Q1/12
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/002 Aftershave preparations
• CPC Class Codes: A61Q 19/004 Aftersun preparations
• CPC Class Codes: A61Q 19/04 for chemically tanning the skin topical sun or radiation screening or tanning preparations A61Q17/04
• CPC Class Codes: A61Q 19/10 Washing or bathing preparations
• CPC Class Codes: A61Q 5/02 Preparations for cleaning the hair
• CPC Class Codes: A61Q 5/06 Preparations for styling the hair, e.g. by temporary shaping or colouring
• CPC Class Codes: A61Q 5/12 Preparations containing hair conditioners
• CPC Class Codes: C07K 14/43563 from insects

Abstract

Use of resilin proteins in cosmetics, wherein the resilin proteins comprise between one and 100 repeat units with the consensus sequence SXXYGXP, where S is a serine, X is any desired amino acid, Y is a tyrosine, G is a glycine and P is a proline.

Claims

1-10. -10. (canceled)

11. A method for producing a cosmetic composition comprising utilizing a resilin protein in the production of a cosmetic composition, wherein the resilin protein comprises between one and 100 repeat units with the consensus sequence SXXYGXP (SEQ ID NO:

4), where S is a serine, X is any amino acid, Y is a tyrosine, G is a glycine, and P is a proline.

12. The method of claim 11, wherein the repeat units comprise the consensus sequence:

13. The method of claim 11, wherein the composition comprises a hybrid protein comprising resilin sequences and sequences of non-resilin-structural proteins.

14. The method of claim 11, wherein the resilin protein is joined to an effector molecule.

15. The method of claim 14, wherein the effector molecule is a UV absorber.

16. The method of claim 11, wherein the resilin protein is used in skin cosmetics.

17. A cosmetic composition comprising at least one resilin protein and at least one active ingredient from the group of UV absorbers.

18. A basic resilin protein, wherein the ratio of basic amino acid radicals (K, R) present in the repeat units which form the resilin protein to acidic amino acid radicals (D, E) is at least 1.5.

19. The basic resilin protein of claim 18, wherein the resilin protein comprises the sequence as set forth in SEQ ID NO:

1.

20. A method of producing the basic resilin protein of claim 18, comprising producing a gene sequence which codes for a repeat unit of a basic resilin protein, combining one or more repeat units to give an overall gene with one or more repeat units, expressing the overall gene in a host organism, and isolating the expressed basic resilin protein from the host organism and/or its culture medium.