Iontophoresis device selecting drug to be administered on the basis of information form sensor

• US 20100016781A1
• Filed: 08/29/2006
• Published: 01/21/2010
• Est. Priority Date: 08/29/2005
• Status: Abandoned Application

• Current Assignee: TTI Ellebeau, Inc. (Ease Asset Management Ltd.)
• Original Assignee: TTI Ellebeau, Inc. (Ease Asset Management Ltd.)
• Inventors: Nakayama, Mizuo, Matsumura, Akihiko, Matsumura, Takehiko, Akiyama, Hidero
• Application Number:
  US11/991,234
• Publication Number:
  US 20100016781A1
• Time in Patent Office: Days
• US Class Current: 604/20
• CPC Class Codes: A61N 1/0444 Membrane
• CPC Class Codes: A61N 1/303 Constructional details electrodes for external use A61N1/0428

Abstract

An iontophoresis device including an electric power source. A first electrode assembly is electrically coupled to the electric power source to transdermally administer an ionic drug to an organism via iontophoresis while a second electrode assembly is electrically coupled to the electric power source as a counter electrode to the first electrode assembly. A sensor may be positioned proximate an internal or external portion of the organism and operable to determine information used to select and deliver the ionic drug to the organism.

Claims

1. An iontophoresis device, comprising:

an electric power source;

a first electrode assembly electrically coupled to the electric power source to transdermally administer an ionic drug to an organism via iontophoresis;

a second electrode assembly electrically coupled to the electric power source as a counter electrode to the first electrode assembly; and

a sensor positioned proximate an internal or external portion of the organism and operable to determine information used to select and transdermally deliver the ionic drug to the organism.

2. The iontophoresis device according to claim 1 wherein the first electrode assembly comprises:

a first electrode electrically coupled to the electric power source to have a same polarity as a component of the ionic drug;

a first electrolyte solution holding portion impregnated with a first electrolyte solution, the first electrolyte solution holding portion disposed adjacent to the first electrode;

a first ion exchange membrane that substantially passes ions having a polarity that is the same as a polarity of the ionic drug and that substantially blocks ions having a polarity that is opposite the polarity of the ionic drug, the ion exchange membrane disposed adjacent to the first electrolyte solution holding portion;

a drug holding portion impregnated with the ionic drug, the drug holding portion disposed adjacent to the first ion exchange membrane; and

a second ion exchange membrane that substantially passes ions having a polarity opposite the polarity of the ionic drug and that substantially blocks ions having a polarity that is the same as a polarity of the ionic drug, the second ion exchange membrane disposed adjacent to the drug holding portion.

3. The iontophoresis device according to claim 2 wherein the second electrode assembly comprises:

a second electrode electrically coupled to the electric power source to have a polarity opposite that of the first electrode;

a second electrolyte solution holding portion impregnated with a second electrolyte solution, the second electrolyte solution holding portion disposed adjacent to the second electrode; and

a third ion exchange membrane that substantially passes ions having a polarity that is the same as a polarity of the ionic drug and that substantially blocks ions having a polarity that is opposite the polarity of the ionic drug, the ion exchange membrane disposed adjacent to the second electrolyte solution holding portion.

4. The iontophoresis device according to claim 1 wherein the first electrode assembly comprises a plurality of electrode assemblies capable of releasing respective ones of a plurality of ionic drugs.

5. The iontophoresis device according to claim 4 wherein the sensor is operable to determine the information used to select and transdermally deliver the respective ones of the plurality of ionic drugs to the organism.