METERED DROP BOTTLE FOR DISPENSING MICROLITER AMOUNTS OF A LIQUID IN THE FORM OF A DROP

• US 20100016814A1
• Filed: 12/07/2007
• Published: 01/21/2010
• Est. Priority Date: 12/07/2006
• Status: Active Grant

• Current Assignee: Sun Pharma Advanced Research Company Limited (Shanghvi Finance Pvt Ltd.)
• Original Assignee: Sun Pharma Advanced Research Company Limited (Shanghvi Finance Pvt Ltd.)
• Inventors: Gokhale, Satish Madhukar, Takale, Abhijit, Kane, Prashant
• Granted Patent: US 8,328,775 B2
• Time in Patent Office: Days
• US Class Current: 604/298
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61F 9/0026 Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: B65D 1/32 Containers adapted to be temporarily deformed by external pressure to expel contents B65D47/2018, B65D83/0055 take precedence ; containers for pharmaceutical purposes A61J1/20, A61M5/19; containers with disinfecting linings A61L2/00; liquid sprayers B05B; oil cans F16N3/00
• CPC Class Codes: B65D 47/18 for discharging drops; Droppers droppers in general B01L3/00; pipettes connected to container closures B01L3/0282

Abstract

The present invention relates to a metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop comprising: (a) a bottle with a flexible portion on the walls to decrease the internal volume by a fixed volume; (b) a plunger with a fixed stroke for depressing the flexible portion of the walls of the bottle; and (c) a nozzle tip having an internal and/or outer diameter no more than 1.2 mm.

Claims

1. A metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop comprising:

(a) a bottle with a flexible portion on the walls to decrease the internal volume by a fixed volume;

(b) a plunger with a fixed stroke for depressing the flexible portion of the walls of the bottle;

(c) a nozzle tip having an internal and/or outer diameter no more than 1.2 mm.

2. A metered drop bottle as in claim 1, wherein the bottle dispenses a drop of predetermined size of about 14 microliter to about 25 microliter of the liquid to be dispensed.

3. A metered drop bottle as in claim 2, wherein the bottle dispenses a drop of predetermined size of about 14 microliter to about 18 microliter of the liquid to be dispensed.

4. A metered drop bottle as in claim 1, wherein the flexible portion is on the sidewalls or the bottom wall of the bottle.

5. A metered drop bottle as in claim 4, wherein the flexible portion on the walls of the bottle is a flexible notch area.

6. A metered drop bottle as in claim 5, wherein the flexible notch area is situated on the sidewalls of the bottle.

7. A metered drop bottle as in claim 6, wherein the flexible notch area is controllably depressed by the plunger by a distance of about 0.8 mm to about 2 mm in order to deliver a predetermined volume of liquid from the bottle to the nozzle.

8. A metered drop bottle as in claim 4, wherein the bottle further comprises an external cover which surrounds the bottle and houses the plunger.

9. A metered drop bottle as in claim 8, wherein the plunger is in-built in the sidewalls of the cover.

10. A metered drop bottle as in claim 8, wherein the plunger is separate from the external cover and is fitted into the external cover before use.

11. A metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop as in claim 1, wherein the bottle further comprises at least one cap.

12. A metered drop bottle as in claim 5, wherein the bottle comprises ribs around the flexible notch area.

13. A metered drop bottle as in claim 8, wherein the bottle further comprises a slot.

14. A metered drop bottle as in claim 8, wherein the external cover comprises a rib for fitting into the slot of the bottle.

15. A metered drop bottle as in claim 8, wherein the external cover is opaque.

16. A metered drop bottle as in claim 8, wherein the bottle is transparent.

17. A metered drop bottle as in claim 1, wherein the bottle further comprises an orientation indicator.

18. A metered drop bottle as in claim 1, wherein the bottle is used for administration of medicament to the eye of a user in need of the medicament.

19. A metered drop bottle as in claim 18, wherein the device further comprises an eyedrop dispensing aid.