Peptides directed for diagnosis and treatment of amyloid-associated diseases
First Claim
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1. A method of treating or preventing an amyloid-associated disease in an individual in need thereof, the method comprising administering to the individual a therapeutically effective amount of a synthetic dipeptide as set forth in SEQ ID NO:
- 145 (D-Trp-Aib), thereby treating or preventing the amyloid-associated disease in the individual.
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Abstract
Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X—Y or Y—X, wherein X is an aromatic amino acid and Y is any amino acid other than glycine. Also provided are pharmaceutical compositions and kits including such peptides as well as methods using same for diagnosing and treating amyloid associated diseases.
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Citations
3 Claims
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1. A method of treating or preventing an amyloid-associated disease in an individual in need thereof, the method comprising administering to the individual a therapeutically effective amount of a synthetic dipeptide as set forth in SEQ ID NO:
- 145 (D-Trp-Aib), thereby treating or preventing the amyloid-associated disease in the individual.
- View Dependent Claims (2, 3)
Specification