Methods and Compositions for the Treatment of CNS-Related Conditions
First Claim
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1. A pharmaceutical composition comprising:
- (a) an NMDA receptor antagonist;
(b) a second agent, wherein said agent is a monoamine oxidase (MAO) inhibitor or a GADPH inhibitor; and
(c) a pharmaceutically acceptable carrierwherein said NMDA receptor antagonist, said second agent, or both are in an extended release dosage form.
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Abstract
The invention provides methods and compositions for the treatment of dementia-related conditions, such as Parkinson'"'"'s disease and Alzheimer'"'"'s disease.
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Citations
55 Claims
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1. A pharmaceutical composition comprising:
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(a) an NMDA receptor antagonist; (b) a second agent, wherein said agent is a monoamine oxidase (MAO) inhibitor or a GADPH inhibitor; and (c) a pharmaceutically acceptable carrier wherein said NMDA receptor antagonist, said second agent, or both are in an extended release dosage form. - View Dependent Claims (2, 4, 8, 9, 14, 15, 16, 17, 18, 19, 22)
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3. (canceled)
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5-7. -7. (canceled)
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10-13. -13. (canceled)
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20-21. -21. (canceled)
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23-26. -26. (canceled)
- 27. A method of treating a CNS-related condition comprising administering to a subject in need thereof a therapeutically effective amount of a combination comprising an NMDA receptor antagonist and a second agent, wherein said second agent is a MAO inhibitor or a GADPH inhibitor.
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29-33. -33. (canceled)
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36-39. -39. (canceled)
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46-53. -53. (canceled)
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55-56. -56. (canceled)
Specification