IMPLANTABLE DRUG DELIVERY SYSTEM

• US 20100022945A1
• Filed: 10/08/2009
• Published: 01/28/2010
• Est. Priority Date: 03/11/2002
• Status: Abandoned Application

• Current Assignee: Novartis Ag
• Original Assignee: Novartis Ag
• Inventors: Rodstrom, Theron Robert
• Application Number:
  US12/575,573
• Publication Number:
  US 20100022945A1
• Time in Patent Office: Days
• US Class Current: 604/22
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61K 9/0051 Ocular inserts, ocular implants
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

An implantable medicament delivery device includes a core body which further includes a single basin or multiple smaller basins for containing a drug or a medicament. Each basin is covered by a screen. The implantable drug delivery device is placed within the body of an animal, and the drug is allowed to diffuse through the holes in the screen to provide treatment of a disease or condition.

Claims

1. A method of making implantable drug delivery platform comprising the steps of:

a) forming a basin containment portion around a basin, said basin being constructed and arranged to contain the drug;

b) affixing a first screen to said basin containment portion to cover said basin.

2. The method as defined in claim 1 further including the step of placing a second screen on the opposite side of said basin.

3. The method as defined in claim 2 wherein said second screen is affixed to said basin containment portion.

4. The method as defined in claim 1 wherein said basin containment portion is substantially planar.

5. The method as defined in claim 1 wherein said first screen is formed to be substantially planar.

6. The method as defined in claim 2 wherein said second screen is formed to be substantially planar.

7. The method as defined in claim 1 wherein the combination of said basin containment portion and said screen are formed to encircle an internal body part.

8. The method as defined in claim 1 wherein the step of forming said screen is further defined by forming the number and size of the holes in said screen depending on one or more factors selected from a group including medicament solubility, medicament dissolution rate, and medicament concentration.

9. The method as defined in claim 1 further including the step of dividing said basin into at least two smaller basins.

10. The method as defined in claim 9 further including the step of forming the size and number of the holes in said screen covering said smaller basins.

11. A method of treating a disease within the eye of an animal, said method comprising the steps of:

making an incision in the sclera;

inserting a drug delivery device through said incision, said drug delivery device including;

a basin containment portion including a basin constructed and arranged to contain the drug;

a screen constructed and arranged to cover said basin and be affixed to said basin containment portion.

12. The method as defined in claim 11 the opposite sides of said basin is formed as a screen.

13. The method as defined in claim 11 wherein said basin passes through said basin containment portion and on the bottom of said basin is a second screen, said second screen being constructed and arranged to cover the basin and be affixed to said basin containment portion.

14. The method as defined in claim 11 wherein said basin containment portion is substantially planar.

15. The method as defined in claim 11 wherein said screen is substantially planar.

16. The method as defined in claim 13 wherein said second screen is substantially planar.

17. The method as defined in claim 11 wherein the size of the holes in said screen is dependent on one or more factors selected from a group including medicament solubility, medicament dissolution rate, and medicament concentration.

18. The method as defined in claim 13 wherein the number and size of the holes in said second screen is dependent on one or more factors selected from a group including medicament solubility, medicament dissolution rate, and medicament concentration.

19. The method as defined in claim 11 wherein said well in said basin containment portion is divided into at least two smaller basins.

20. The method as defined in claim 17 wherein the size and number of the holes in said screen covering said smaller basins are different.