SYSTEM AND METHOD FOR MAINTAINING A DISTRIBUTION OF CURRENTS IN AN ELECTRODE ARRAY USING INDEPENDENT VOLTAGE SOURCES

• US 20100023070A1
• Filed: 07/23/2009
• Published: 01/28/2010
• Est. Priority Date: 07/24/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Moffitt, Michael, Peterson, David K.L.
• Granted Patent: US 8,131,358 B2
• Time in Patent Office: Days
• US Class Current: 607/2
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain

Abstract

In one technique, a desired electrical current distribution on at least three active electrodes is selected. An electrical energy perturbation is generated on at least one electrode. A current-to-voltage relationship at each active electrode is estimated based on the energy perturbation. The current-to-voltage relationship for each active electrode takes into account current flow through other active electrodes. The voltage distribution necessary to achieve the desired current distribution is determined based on the estimated current-to-voltage relationship. Voltage-regulated energy is conveyed between the electrodes and tissue in accordance with the determined electrical voltage distribution. In another technique, an electrical energy perturbation on at least one of the electrodes is generated. Network resistances for each of at least three active electrodes are computed in response to the energy perturbation. The network resistances represent the resistances between the electrodes and common node to which the electrodes are connected.

Claims

1-36. -36. (canceled)

37. A method of performing a medical procedure using a plurality of electrodes implanted within tissue of a patient, comprising:

generating an electrical energy perturbation on at least one of the plurality of electrodes; and

computing network resistances for each of at least three active ones of the electrodes in response to the electrical energy perturbation, wherein the network resistances represent the resistances between the respective active electrodes and a common node to which the active electrodes are connected in parallel.

38. The method of claim 37, wherein the electrical energy perturbation is a voltage-regulated perturbation.

39. The method of claim 37, wherein the electrical energy perturbation creates a change in voltage drop between two of the active electrodes and a change in electrical current between the two active electrodes, and wherein the computation of the network resistance for each of the two active electrodes comprises dividing a change in voltage on the respective active electrode by the change in the electrical current between the two electrodes.

40. The method of claim 39, wherein the change in voltage drop between the two active electrodes maintains a voltage at the common node at the same value.

41. The method of claim 40, wherein the generation of the electrical energy perturbation comprises generating oppositely polarized pulses at the two active electrodes.

42. The method of claim 37, further comprising measuring interelectrode impedances between the active electrodes in response to generating the electrical energy perturbation, wherein the network resistances are computed based on the measured interelectrode impedances.

43. The method of claim 42, wherein each interelectrode impedance for a respective active electrode is computed by summing interelectrode impedances between each respective active electrode and two of the other active electrodes, subtracting the interelectrode impedance between the other two active electrodes from the sum, and dividing the result by two.

44. The method of claim 37, further comprising determining an electrical voltage distribution on the active electrodes necessary to achieve a desired electrical current distribution on the active electrodes, or determining an electrical current distribution on the active electrodes necessary to achieve a desired voltage distribution on the active electrodes, wherein the electrical voltage distribution or electrical current distribution is based on the computed network resistances.

45. The method of claim 37, further comprising conveying electrical stimulation energy between the active electrodes and the tissue, wherein the network resistances are computed at a zero operating point of the conveyed electrical stimulation energy.

46. The method of claim 45, wherein the electrical energy perturbation is generated in the absence of the conveyed electrical stimulation energy.

47. The method of claim 37, further comprising conveying electrical stimulation energy between the active electrodes and the tissue, wherein the network resistances are computed at a non-zero operating point of the conveyed electrical stimulation energy.

48. The method of claim 47, wherein the electrical energy perturbation is generated during the conveyance of the electrical stimulation energy.

49. A neurostimulation system, comprising:

a plurality of electrodes configured for being placed in contact with tissue;

analog output circuitry configured generating an electrical energy perturbation on at least one of the plurality of electrodes; and

processing circuitry configured for computing network resistances for each of at least three active ones of electrodes in response to the electrical energy perturbation, wherein the network resistances represent the resistances between the respective active electrodes and a common node to which the active electrodes are connected in parallel.

50. The neurostimulation system of claim 49, wherein the electrical energy perturbation is a voltage-regulated perturbation.

51. The neurostimulation system of claim 49, wherein the electrical energy perturbation creates a change in voltage drop between two of the active electrodes and a change in electrical current between the two active electrodes, and wherein the processing circuitry is configured for computing the network resistance for each of the two active electrodes by dividing a change in voltage on the respective active electrode by the change in the electrical current between the two active electrodes.

52. The neurostimulation system of claim 51, wherein the change in voltage drop between two of the active electrodes maintains a voltage at the common node at the same value.

53. The neurostimulation system of claim 52, wherein the generation of the electrical energy perturbation comprises generating oppositely polarized pulses at the two active electrodes.

54. The neurostimulation system of claim 49, further comprising monitoring circuitry configured for measuring interelectrode impedances between the active electrodes in response to the analog output circuitry generating the electrical energy perturbation, wherein the processing circuitry is configured for computing the network resistances based on the measured interelectrode impedances.

55. The neurostimulation system of claim 54, wherein the processing circuitry is configured for computing each interelectrode impedance for a respective active electrode by summing interelectrode impedances between each respective active electrode and two of the other active electrodes, subtracting the interelectrode impedance between the other two active electrodes from the sum, and dividing the result by two.

56. The neurostimulation system of claim 49, wherein the processing circuitry is further configured for determining an electrical voltage distribution on the active electrodes necessary to achieve a desired electrical current distribution on the active electrodes, or determining an electrical current distribution on the active electrodes necessary to achieve a desired voltage distribution on the active electrodes, wherein the electrical voltage distribution or electrical current distribution is based on the computed network resistances.

57. The neurostimulation system of claim 49, wherein the analog output circuitry is further configured for conveying electrical stimulation energy between the active electrodes and the tissue, and wherein the processing circuitry is configured for computing the network resistances at a zero operating point of the conveyed electrical stimulation energy.

58. The neurostimulation system of claim 57, wherein the analog output circuitry is configured for generating the electrical energy perturbation in the absence of the conveyed electrical stimulation energy.

59. The neurostimulation system of claim 49, wherein the analog output circuitry is further configured for conveying electrical stimulation energy between the active electrodes and the tissue, and wherein the processing circuitry is configured for computing the network resistances at a non-zero operating point of the conveyed electrical stimulation energy.

60. The neurostimulation system of claim 59, wherein the analog output circuitry is configured for generating the electrical energy perturbation during the conveyance of the electrical stimulation energy.

61. The neurostimulation system of claim 49, further comprising an implantable neurostimulator containing the analog output circuitry, and an external controller containing the processing circuitry.