Systems and Methods for Simultaneously Treating Multiple Target Sites

• US 20100030076A1
• Filed: 07/27/2009
• Published: 02/04/2010
• Est. Priority Date: 08/01/2006
• Status: Abandoned Application

• Current Assignee: InSightec Ltd.
• Original Assignee: InSightec Ltd.
• Inventors: Prus, Oleg, Vitek, Shuki, Vortman, Kobi
• Application Number:
  US12/509,907
• Publication Number:
  US 20100030076A1
• Time in Patent Office: Days
• US Class Current: 600/439
• CPC Class Codes: A61B 17/22004 using mechanical vibrations, e.g. ultrasonic shock waves A61B17/225 takes precedence
• CPC Class Codes: A61B 2017/22028 arrays, e.g. phased arrays
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 2007/0095 by modifying an excitation signal
• CPC Class Codes: A61N 2007/027 with multiple foci created simultaneously
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: G01S 15/8925 the array being a two-dimensional transducer configuration, i.e. matrix or orthogonal linear arrays
• CPC Class Codes: G01S 7/52019 Details of transmitters
• CPC Class Codes: G01S 7/5209 using multibeam transmission
• CPC Class Codes: G10K 11/346 using phase variation

Abstract

The emission intensities of groupings of transducer elements of an ultrasound transducer array are controlled based on targeting criteria in such a manner as to simultaneously create multiple discontiguous foci, each corresponding to one of a plurality of target sites.

Claims

1. A system for delivering acoustic energy to a plurality of target sites within a patient, the system comprising:

a transducer array comprising a plurality of transducers each transmitting acoustic energy to a respective focus, the foci being discontiguous and forming a pattern of target sites;

a processor coupled to the array for establishing targeting criteria corresponding to the pattern; and

a controller coupled to the processor and the transducers, the controller driving the transducer elements based at least in part on the targeting criteria.

2. The system of claim 1 wherein each transducer comprises a plurality of grouped transducer elements, the element groupings being based on the targeting criteria.

3. The system of claim 1 wherein the targeting criteria comprise one or more of steering angles of the transducers with respect to each of the target sites, lines of sight from the transducers to each of the target sites, anatomical features of the patient, locations of the target sites within the patient or transducer elements shapes and dimensions.

4. The system of claim 3 wherein each group of transducer elements is controllable independently of the other groups.

5. The system of claim 4 wherein the transducer element groups are mechanically connected.

6. The system of claim 4 wherein the transducer element groups are flexibly connected.

7. The system of claim 4 further comprising a single beamformer for driving each of the transducer element groups.

8. The system of claim 4 further comprising a plurality of beamformers, each driving one of the transducer element groups.

9. The system of claim 3 wherein the element groupings are defined such that the lines of sight from each element group to its corresponding target site do not pass through a previously-identified no-pass region.

10. The system of claim 3 wherein the element groupings are defined such that any overlap of the lines of sight from each element group to its corresponding target site remains below an overlap threshold.

11. The system of claim 1 wherein the controller drives the transducer elements such that the acoustic energy is delivered to the foci in rapid switching fashion.

12. The system of claim 1 wherein each of the element groups produces ultrasound energy at different frequencies.

13. The system of claim 1 wherein each of the element groups has a preset focal length.

14. The system of claim 1 further comprising an imager for capturing images of the multiple target sites.

15. The system of claim 14 wherein the imager comprises a plurality of imaging devices, thereby simultaneously generating multiple images of the target sites.

16. The system of claim 14 wherein the imager comprises a single imaging device for generating a sequence of images capturing multiple images of the target sites.

17. The system of claim 14 wherein the imager comprises a single imaging device configured to generate a single image capturing multiple images of the target sites.

18. A method for simultaneously delivering focused ultrasound to a plurality of discontiguous target sites, the method comprising:

providing an ultrasound transducer array comprising a plurality of transducer elements;

determining one or more targeting criteria for each element with respect to the target sites;

determining element groupings based on the targeting criteria; and

driving the transducer elements based upon the respective element groupings to simultaneously focus acoustic energy transmitted by the transducer elements at the plurality of target sites.

19. The method of claim 18 further comprising mechanically connecting a plurality of independent transducer arrays to form the ultrasound transducer array.

20. The method of claim 18 wherein the transducer elements are driven in rapid switching fashion such.

21. The method of claim 18 wherein the targeting criteria comprise one or more of steering angles of the transducer elements with respect to each of the target sites, lines of sight from the transducer elements to each of the target sites, or f-numbers of the transducer elements groupings.

22. The method of claim 21 further comprising defining a no-pass region through which no ultrasound energy is permitted to pass and wherein the element groupings are determined such that the lines of sight from each element grouping to its corresponding target site do not pass through the no-pass region.

23. The method of claim 21 wherein the element groupings are defined such that any overlap of the lines of sight from each element grouping to its corresponding target site remains below an overlap threshold.

24. The method of claim 18 further comprising capturing one or more images of the target zones.