Device and method for mitral valve repair

• US 20100030330A1
• Filed: 08/01/2008
• Published: 02/04/2010
• Est. Priority Date: 08/01/2008
• Status: Abandoned Application

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Popp, Michael, Rowe, Stanton, Yi, Seung, Bobo, Donald E.
• Application Number:
  US12/221,450
• Publication Number:
  US 20100030330A1
• Time in Patent Office: Days
• US Class Current: 623/2.360
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2442 Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
• CPC Class Codes: A61F 2/2451 Inserts in the coronary sinus for correcting the valve shape
• CPC Class Codes: A61F 2/2454 Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
• CPC Class Codes: A61F 2/2487 Devices within the heart chamber, e.g. splints

Abstract

Devices and methods for reshaping a mitral valve annulus are provided. One device according to the invention is configured for deployment in the right atrium and is shaped to apply a force along the atrial septum. The device causes the atrial septum to deform and push the anterior leaflet of the mitral valve in a posterior direction for reducing mitral valve regurgitation. Another embodiment of a device is deployed in the left ventricular outflow tract at a location adjacent the aortic valve. The device may be expandable for urging the anterior leaflet toward the posterior leaflet. Another embodiment of the device includes a first anchor, a second anchor, and a bridge, with the bridge having sufficient length to reach from the coronary sinus to the right atrium and/or superior or inferior vena cava. In a further embodiment a device includes a middle anchor positioned on the bridge between the distal and proximal anchors.

Claims

1. An implant for placement in a heart of a patient, comprising:

a first anchor configured to be secured to tissue in a coronary sinus;

a second anchor configured to be secured to tissue in a right atrium; and

a bridge extending from the first anchor to the second anchor.

2. The implant of claim 1, wherein the first anchor comprises a radially expandable and generally cylindrical structure.

3. The implant of claim 1, wherein the second anchor comprises one or more barbs configured to engage atrial tissue

4. The implant of claim 1, wherein the second anchor comprises an expandable mesh-like structure.

5. The implant of claim 1, wherein the first anchor is configured to be deployed in a distal portion of the coronary sinus, and the bridge has sufficient length to extend from the distal portion of the coronary sinus to the right atrium.

6. The implant of claim 1, wherein a length along the bridge between the first anchor and second anchor is 40 mm to 150 mm.

7. The implant of claim 6, wherein one or more of the anchors is configured to be advanced along a portion of the bridge.

8. An implant for placement in a heart of a patient, comprising:

a first anchor configured to be secured to cardial tissue;

a second anchor configured to be secured to tissue in a vena cava; and

a bridge extending from the first anchor to the second anchor.

9. The implant of claim 8, wherein the first anchor is configured to be secured to tissue in a coronary sinus.

10. The implant of claim 9, wherein the first anchor comprises a radially expandable generally cylindrical structure.

11. The implant of claim 9, wherein the bridge has sufficient length to extend from a distal portion of the coronary sinus to an inferior vena cava.

12. The implant of claim 9, wherein the bridge has sufficient length to extend from the distal portion of the coronary sinus to a superior vena cava.

13. The implant of claim 9, wherein the second anchor is configured to be secured to tissue in an inferior vena cava, and the first anchor is configured to be secured to tissue in a superior vena cava.

14. A method of repairing a mitral valve, comprising:

obtaining an implant having a first anchor, a second anchor, and a bridge connecting the first anchor to the second anchor;

deploying the first anchor in a first portion of the heart; and

deploying the second anchor in a second portion of the heart such that the bridge engages against an atrial septum with sufficient force to reshape an annulus of the mitral valve.

15. The method of claim 14, wherein the second portion of the heart is in the right atrium.

16. The method of claim 14, wherein the second portion of the heart is an inferior vena cava.

17. The method of claim 14, wherein the second portion of the heart is a superior vena cava.

18. The method of claim 17, wherein the first portion of the heart is an inferior vena cava.

19. The method of claim 14, wherein the first portion of the heart is a coronary sinus.

20. An implant for placement in a heart of a patient, comprising:

a distal anchor configured to be secured to tissue in a coronary sinus;

a middle anchor configured to be secured to heart tissue;

proximal anchor configured to be secured to heart tissue outside of the coronary sinus;

a distal bridge portion extending from the distal anchor to the middle anchor; and

a proximal bridge portion extending from the middle anchor to the proximal anchor.

21. The implant of claim 20, wherein the distal anchor is configured to be secured to tissue in a distal portion of the coronary sinus, and the middle anchor is configured to be secured to tissue at or adjacent the coronary ostium.

22. The implant of claim 20, wherein the middle anchor is configured to be secured to tissue at or adjacent the coronary ostium, and the proximal anchor is configured to be secured to tissue in a vena cava.

24. The implant of claim 20, wherein the distal bridge portion and proximal bridge portion form a generally continuous bridge structure.

25. The implant of claim 24, wherein the middle anchor is configured to be slidingly moved along the generally continuous bridge structure.

26. The implant of claim 20, wherein the proximal anchor is configured to be slidingly moved along the proximal bridge portion.

27. A method of treating a mitral valve in a patient'"'"'s heart, comprising:

obtaining an implant having a distal anchor, middle anchor, and proximal anchor, with a distal anchor portion extending from the distal anchor to the middle anchor, and a proximal anchor portion extending from the middle anchor to the proximal anchor;

deploying the distal anchor in a coronary sinus;

deploying the middle anchor in the heart; and

deploying the proximal anchor in the heart.

28. The method of claim 27, wherein deploying the middle anchor comprises deploying the middle anchor at or adjacent the coronary sinus ostium.

29. The method of claim 28, wherein deploying the distal anchor comprises deploying the distal anchor in a distal portion of the coronary sinus.

30. The method of claim 27, wherein deploying the proximal anchor comprises deploying the proximal anchor in the right atrium.

31. The method of claim 27, wherein deploying the proximal anchor comprises deploying the proximal anchor in a superior vena cava.

32. The method of claim 27, wherein deploying the proximal anchor comprises deploying the proximal anchor in an inferior vena cava.

33. The method of claim 27, wherein the proximal bridge portion and distal bridge portion connect to form a generally continuous bridge structure, and the method further comprising:

slidingly moving the middle anchor along the bridge structure.

34. The method of claim 27, further comprising:

slidingly moving the proximal anchor along the proximal bridge portion.

35. The method of claim 27, wherein the distal bridge portion defines a length between the distal anchor and middle anchor, and the method further comprising:

adjusting the length between the distal anchor and middle anchor.

36. The method of claim 27, wherein the proximal bridge portion defines a length between the proximal anchor and middle anchor, and the method further comprising:

adjusting the length between the proximal anchor and middle anchor.