Cross-linked polysaccharide gels
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Abstract
The present invention relates to a process for preparing a cross-linked polysaccharide gel comprising contacting a polysaccharide with a cross-linking agent and a masking agent to form a cross-linked polysaccharide gel having resistance to degradation under physiological conditions.
85 Citations
58 Claims
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1-28. -28. (canceled)
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29. A process for preparing a cross-linked polysaccharide gel having resistance to enzymatic degradation under physiological conditions, the process comprising:
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contacting a polysaccharide with a cross-linking agent under conditions to form a cross-linked polysaccharide gel, and contacting the polysaccharide with a masking agent selected from the group consisting of a monofunctional epoxide and an alkyl vinyl sulfone; so as to form a cross-linked polysaccharide gel having resistance to enzymatic degradation. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58)
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Specification