METABOLIC MEASURE SYSTEM INCLUDING A MULTIPLE FUNCTION AIRWAY ADAPTER
First Claim
1. A metabolic measurement system (300) comprising:
- (a) an airway adapter (20, 100, 200, 334) adapted to be coupled in series with a mainstream gas flow comprising;
(1) a housing have a bore (34) defined therethrough to carry the mainstream gas flow through the airway adapter,(2) a window (40) defined in the housing providing optical access to the gas flow through the airway adapter, and(3) an opening (234) defined in the housing providing optical access to the gas flow through the airway adapter;
(b) a sensor head (22, 334) adapted to be removably attached to the airway adapter, the sensor head comprising;
(1) an infrared sensing system adapted to transmit or receive infrared through the window, and(2) a luminescence quenching system adapted to (i) transmit excitation radiation through the opening, (ii) receive emitted radiation from a luminescence material through the opening, or both (i) and (ii);
(c) a flow measurement system (310, 352) adapted to be coupled in series with such a mainstream gas flow; and
(d) a processor (320, 330) adapted to receive signals from the infrared sensing system, the luminescence quenching system, and the flow measurement system, wherein the processor is adapted to determine a metabolic parameter including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), resting energy expenditure (REE), or any combination thereof.
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Accused Products
Abstract
A system (300) for measuring a metabolic parameter. The system includes an integrated airway adapter (20, 100, 200) capable of monitoring any combination of respiratory flow, O2 concentration, and concentrations of one or more of CO2, N2O, and an anesthetic agent in real time, breath by breath. Respiratory flow may be monitored with differential pressure flow meters under diverse inlet conditions through improved sensor configurations which minimize phase lag and dead space within the airway. Molecular oxygen concentration may be monitored by way of luminescence quenching techniques. Infrared absorption techniques may be used to monitor one or more of CO2, N2O, and anesthetic agents.
48 Citations
55 Claims
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1. A metabolic measurement system (300) comprising:
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(a) an airway adapter (20, 100, 200, 334) adapted to be coupled in series with a mainstream gas flow comprising; (1) a housing have a bore (34) defined therethrough to carry the mainstream gas flow through the airway adapter, (2) a window (40) defined in the housing providing optical access to the gas flow through the airway adapter, and (3) an opening (234) defined in the housing providing optical access to the gas flow through the airway adapter; (b) a sensor head (22, 334) adapted to be removably attached to the airway adapter, the sensor head comprising; (1) an infrared sensing system adapted to transmit or receive infrared through the window, and (2) a luminescence quenching system adapted to (i) transmit excitation radiation through the opening, (ii) receive emitted radiation from a luminescence material through the opening, or both (i) and (ii); (c) a flow measurement system (310, 352) adapted to be coupled in series with such a mainstream gas flow; and (d) a processor (320, 330) adapted to receive signals from the infrared sensing system, the luminescence quenching system, and the flow measurement system, wherein the processor is adapted to determine a metabolic parameter including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), resting energy expenditure (REE), or any combination thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A metabolic measurement system (300) comprising:
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(a) an airway adapter (20, 100, 200, 334) adapted to be coupled in series with a mainstream gas flow comprising; (1) a housing have a bore (34) defined therethrough to carry the mainstream gas flow through the airway adapter, (2) a window (40) defined in the housing providing optical access to the gas flow through the airway adapter, and (3) an opening (234) defined in the housing providing optical access to the gas flow through the airway adapter; (b) a sensor head (22, 334) adapted to be removably attached to the airway adapter, the sensor head comprising; (1) an infrared sensing system adapted to transmit or receive infrared through the window, and (2) an oxygen sensing system associated with the opening and adapted to provide a signal indicative of a concentration of oxygen in the gas flow; (c) a flow measurement system (310, 352) adapted to be coupled in series with such a mainstream gas flow; and (d) a processor (320, 330) adapted to receive signals from the infrared sensing system, the luminescence quenching system, and the flow measurement system, wherein the processor is adapted to determine a metabolic parameter including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory quotient (RQ), resting energy expenditure (REE), or any combination thereof. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30)
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31. An airway adapter (20, 100, 200, 334)) comprising:
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a housing having a bore formed therethrough adapted to carry a flow of gas through the housing; a flow detection assembly associated with the housing; a first gas constituent detection assembly associated with the housing and adapted to sense a first constituent of the flow of gas without diverting gas from the housing, wherein the first gas constituent detection assembly includes a detection chamber defined within the housing, and wherein a boundary of the detection chamber is defined, at least partially, by a window; and a second gas constituent detection assembly component associated with the housing to sense a second constituent of the flow of gas without diverting gas from the housing, wherein the second gas constituent detection assembly includes an opening defined in the housing, and a gas sensor having a least a portion disposed in the opening, wherein a first output of the flow detection assembly provides first data indicative of a gas flow through the housing, wherein a second output of the first gas constituent detection assembly provides second data indicative of the first gas constituent, and wherein a third output of the second gas constituent detection assembly provides third data indicative of the second gas constituent, and wherein the first data, the second data, and the third data are provided substantially simultaneously. - View Dependent Claims (32, 33, 34, 35, 36, 37)
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38. A metabolic measurement system (300) comprising:
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(a) an airway adapter (20, 100, 200, 334) adapted to be coupled in series with a mainstream gas flow comprising; (1) a housing having a bore formed therethrough adapted to carry the mainstream gas flow through the housing, (2) a detection chamber (34, 34′
, 114) defined within the housing, and wherein a boundary of the detection chamber is defined, at least partially, by a window adapted to provide optical access to the mainstream gas flow through the housing,(3) an opening (40, 234) defined in the housing, and (4) a gas sensor having a least a portion disposed in the opening; (b) a sensor head (22, 334) adapted to be removably attached to the airway adapter, the sensor head comprising; (1) an infrared sensing system adapted to transmit or receive infrared through the window, wherein the detection chamber, the window, and the infrared sensing system define a first gas constituent detection assembly adapted to detect a first constituent of the mainstream gas flow without diverting any portion of the mainstream gas flow from the housing, (2) an oxygen sensing system associated with the opening and adapted to provide a signal indicative of a concentration of oxygen in the gas flow, wherein the opening, the gas sensor and the oxygen sensing system define a second gas constituent detection assembly adapted to detect a second constituent of the mainstream gas flow without diverting any portion of the mainstream gas flow from the housing; (c) a flow measurement system (310, 352) adapted to be coupled in series with such a mainstream gas flow; and (d) a processor (320, 330) adapted to receive signals from the infrared sensing system, the oxygen sensing system, and the flow measurement system. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46)
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47. An airway adapter (20, 100, 200, 334) comprising:
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a housing having an inlet, and outlet, and a bore formed therethrough, wherein a flow of gas enters the inlet, is carried through the housing via the bore, and exits the outlet, and wherein a volume of the flow of gas entering the inlet corresponds to a volume of the flow of gas exiting the outlet such that no gas is exhausted from the bore between the inlet and the outlet; a flow detection assembly associated with the housing; a first gas constituent detection assembly associated with the housing and adapted to sense a first constituent of the flow of gas without diverting gas from the housing, wherein the first gas constituent detection assembly includes a detection chamber defined within the housing, and wherein a boundary of the detection chamber is defined, at least partially, by a window; and a second gas constituent detection assembly component associated with the housing to sense a second constituent of the flow of gas, wherein the second gas constituent detection assembly includes a gas sensor in fluid communication with the flow of gas, wherein a first output of the flow detection assembly provides first data indicative of a gas flow through the housing, wherein a second output of the first gas constituent detection assembly provides second data indicative of the first gas constituent, and wherein a third output of the second gas constituent detection assembly provides third data indicative of the second gas constituent, and wherein the first data, the second data, and the third data are provided substantially simultaneously. - View Dependent Claims (48, 49, 50, 51, 52, 53, 54, 55)
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Specification