AUTO INJECTOR

• US 20100036319A1
• Filed: 01/28/2008
• Published: 02/11/2010
• Est. Priority Date: 02/01/2007
• Status: Abandoned Application

• Current Assignee: PA Knowledge Limited
• Original Assignee: PA Knowledge Limited
• Inventors: Jennings, Douglas Ivan, Corrigan, Joseph Peter, Barrow-Williams, Timothy Donald, Lee, Rosalind Trudy, Cooper, Stuart David, Drake, David, Whitaker, David
• Application Number:
  US12/525,348
• Publication Number:
  US 20100036319A1
• Time in Patent Office: Days
• US Class Current: 604/135
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 2200/10 Coring prevention means, e.g. for plug or septum piecing members
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

An auto injector including: a housing; an outlet portion with a needle (110) moveable relative to the housing; a container (104) within the housing for containing medicament; and an actuatable deployment mechanism configured to deploy the outlet portion by moving the outlet portion relative to the housing and to eject medicament contained in the container through the outlet portion. The auto injector is configured to store a volume of fluid and includes a filling mechanism configured to expel the volume of fluid from the outlet portion and subsequently to draw medicament through the outlet portion and into the container. An adaptor (112) fits to the auto injector so as to cover the needle and includes a puncture member configured to puncture a vial, the puncture member providing fluid communication to the needle. The auto injector and adaptor are provided as part of an auto injector pack together with a vial containing a substance which in combination with the liquid forms the medicament and a casing configured to house the vial, the auto injector and the adaptor

Claims

1. An auto injector including:

a housing;

an outlet portion moveable relative to the housing;

a container within the housing for containing medicament;

an actuatable deployment mechanism configured to deploy the outlet portion by moving the outlet portion relative to the housing and to eject medicament contained in the container through the outlet portion;

wherein;

the auto injector includes;

a filling mechanism configured to draw medicament through the outlet portion and into the container.

2. An auto injector according to claim 1 wherein the outlet portion includes a passageway.

3. An auto injector according to claim 2 wherein the outlet portion is configured to hold a needle such that the needle is in fluid communication with the passageway.

4. An auto injector according to claim 3 wherein the outlet portion includes the needle in fluid communication with the passageway.

5. An auto injector according to claim 2 wherein the container is in fluid communication with the passageway.

6. An auto injector according to claim 1 wherein the container includes:

walls defining an elongate bore extending from a container outlet; and

a piston sealing with the walls and slidable along the bore.

7. An auto injector according to claim 6 wherein the deployment mechanism is configured to eject medicament contained in the container by sliding the piston along the bore towards the container outlet.

8. An auto injector according to claim 6, wherein the filling mechanism is configured to draw medicament into the container by sliding the piston along the bore away from the container outlet.

9. An auto injector according to any preceding claim 1 wherein the filling mechanism includes a filling member moveable by a user from a first position to a second position to draw medicament through the outlet portion and into the container.

10. An auto injector according to claim 9 wherein the filling member is configured as a sleeve around the housing and is configured to slide along the housing from the first position to the second position.

11. An auto injector according to any preceding claim 1 wherein the deployment mechanism includes a user actuatable deployment actuator configured to actuate the deployment mechanism.

12. An auto injector according to claim 11 wherein the filling mechanism includes a lock out component for preventing operation of the user actuatable deployment actuator until the filling mechanism has drawn medicament into the container.

13. An auto injector according to claim 12 wherein the filling member is configured to cover the user actuatable actuator member in the first position and to expose the user actuatable deployment actuator in the second position.

14. An auto injector according to claim 1 wherein the auto injector is configured to store a volume of fluid and the filling mechanism is configured to expel the volume of fluid from the outlet portion before drawing medicament through the outlet portion and into the container.

15. An auto injector according to claim 14 wherein the container is configured to store the volume of the fluid.

16. An auto injector according to claim 15 further including water stored in the container.

18. An auto injector according to any one of claims 14 to 17claim 14 further including:

an internal power source configured to power the filling mechanism to expel the volume of fluid.

19. An auto injector according to claim 18 wherein said power source is additionally configured to power the deployment mechanism.

20. An auto injector according to claim 18 wherein said power source is a spring.

21. An auto injector according to any one of claims 11 to 20claim 14 wherein the filling mechanism includes a user actuatable filling actuator configured to actuate the filling mechanism to expel the volume of fluid.

40. An auto injector according to claim 1

wherein the container includes walls defining an elongate bore extending from a container outlet, and a piston sealing with the walls and slidable along the bore;

and

wherein the auto injector is configured to store a volume of fluid and the filling mechanism is configured to expel the volume of fluid from the outlet portion before drawing medicament through the outlet portion and into the container; and

wherein the filling mechanism is configured to expel the volume of fluid by sliding the piston along the bore towards the container outlet.

17. (canceled)

22. An adaptor for use with an auto injector having a container having an elongate body with an injection end from which a needle extends to a needle tip, the adaptor including:

a housing arranged to mount on and seal with the container so as to define with the container a cavity within which the needle of the container can extend without the needle tip contacting the housing; and

a puncture member extending from the housing, arranged to puncture a septum of a vial sealing an interior of the vial and having at least one port arranged to provide fluid communication between the interior of the vial and the cavity.

23. An adaptor according to claim 22 wherein the housing includes a mounting portion for fitment to a housing of the auto injector to secure the adaptor to the auto injector.

24. An adaptor according to claim 23 wherein the mounting portion includes a collar for fitment to the housing of the auto injector and the housing of the adaptor extends within the collar to mount on and seal with the container of the auto injector.

25. An adaptor according to claim 23 wherein the mounting portion includes one of a bayonet fitting and a threaded fitting.

26. An auto injector set including:

an auto injector having a needle with which to inject medicament and

an adaptor configured to fit to the auto injector so as to cover the needle, the adaptor including a puncture member configured to puncture a vial, the puncture member providing fluid communication to the needle.

27. An auto injector set according to claim 26 wherein the adaptor includes a housing arranged to mount on and seal with the container so as to define with the container a cavity within which the needle of the container can extend without the needle tip contacting the housing;

and wherein the puncture member extends from the housing, is arranged to puncture a septum of the vial sealing an interior of the vial and has at least one port arranged to provide fluid communication between the interior of the vial and the cavity.

28. An auto injector set according to claim 27 wherein the housing of the auto injector includes a receiving portion on which to fit the adaptor.

29. An auto injector according to claim 28 wherein the receiving portion includes one of a bayonet fitting and a threaded fitting.

30. An auto injector set according to claim 26 wherein the auto injector comprises:

a housing;

an outlet portion moveable relative to the housing;

a container within the housing for containing medicament;

an actuatable deployment mechanism configured to deploy the outlet portion by moving the outlet portion relative to the housing and to eject medicament contained in the container through the outlet portion; and

a filling mechanism configured to draw medicament through the outlet portion and into the container.

31. An auto injector pack including:

an auto injector set according to claim 26;

a vial containing a substance which in combination with said liquid forms the medicament; and

a casing configured to house the vial and also the auto injector and adaptor of the auto injector set.

32. An auto injector pack according to claim 31 wherein:

the casing includes a pre-sealed and sterilised section containing the vial and adaptor.

33. An auto injector pack according to claim 31 wherein:

the casing includes a lower portion having a shape to hold each of the auto injector, the vial and the adaptor individually, the lower portion having a shape to hold the adaptor facing outwardly so as to receive the needle of the auto injector and to hold the vial facing outwardly so as to receive the puncture member.

34. An auto injector pack according to claim 31 wherein:

the lower portion has a shape to hold the vial and the adaptor together as an assembled unit after the assembled unit has been detached from the auto injector.

35. An auto injector pack according to claim 31 wherein:

the lower portion has the form of a tray, the auto injector extends along an axis from the needle to an actuator end and the lower portion has a shape to hold the auto injector with the axis of the auto injector within the tray.

36. An auto injector pack according to claim 35 wherein the casing includes a presentation mechanism configured to lift the actuation end of the auto injector out of the lower portion upon opening of the casing.

37. An auto injector pack according to claim 35 wherein:

the lower portion is shaped to hold the actuation end of the auto injector with the auto injector orientated substantially perpendicular to the tray.

38. An auto injector pack according to claim 31 wherein the casing includes an upper portion forming a cover openable with respect to the lower portion.

39. A method of preparing the auto injector of the auto injector pack of claim 31, the method including:

removing the auto injector from the casing;

fitting the auto injector to the adaptor while the adaptor is in the casing;

removing the adaptor from the casing while fitted to the auto injector;

while the vial is in the casing, puncturing the vial with the puncture member of the adaptor and ejecting said fluid from the auto injector through the adaptor into the vial;

removing the vial from the casing while fitted to the adaptor and the auto injector;

re-orientating the auto injector and fitting the auto injector to the casing with the vial and adaptor above the auto injector;

withdrawing the medicament formed in the vial through the adaptor and into the auto injector; and

removing the adaptor and vial from the auto injector.