Cardiovascular Devices and Methods

• US 20100036481A1
• Filed: 06/05/2009
• Published: 02/11/2010
• Est. Priority Date: 04/27/1998
• Status: Abandoned Application

• Current Assignee: Artemis Medical, Inc. (Johnson & Johnson)
• Original Assignee: Artemis Medical, Inc. (Johnson & Johnson)
• Inventors: Fulton, Richard Eustis III, Dubrul, William R.
• Application Number:
  US12/479,375
• Publication Number:
  US 20100036481A1
• Time in Patent Office: Days
• US Class Current: 623/1.420
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61L 2300/416 Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1081 having sheaths or the like for covering the balloon but not forming a permanent part of the balloon, e.g. retractable, dissolvable or tearable sheaths
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: A61N 1/306 Arrangements where at least part of the apparatus is introduced into the body
• CPC Class Codes: A61N 1/327 for enhancing the absorption properties of tissue, e.g. by electroporation

Abstract

A material in a flowable state is applied to the interstitial pores of a radially-expandable endovascular tubular braid structure to modify the tubular braid structure for use in the treatment of cardiovascular disease. The material is cured to form a membrane at least within the coated interstitial pores. A cardiovascular device, for use in a vascular lumen within a body for treatment of cardiovascular disease, includes a braided body with electroporation means for helping prevent restenosis in a cardiovascular lumen. A method for treating cardiovascular disease includes placing a radially expandable and collapsible medical device within a cardiovascular passageway, positioning it at a target site, and placing it in a radially expanded state. Restenosis at the target site is inhibited by a chosen one of electroporation and iontophoresis. The medical device is collapsed and is then removed from the passageway.

Claims

1. A method for modifying a radially-expandable endovascular tubular braid structure, used in the treatment of cardiovascular disease, comprising:

applying a material in a flowable state to the interstitial pores of a radially-expandable endovascular tubular braid structure used in the treatment of cardiovascular disease; and

curing the material to form a membrane at least within the coated interstitial pores.

2. A cardiovascular device, for use in a vascular lumen within a body for treatment of cardiovascular disease, comprising:

a braided body; and

said braided body comprising electroporation means for helping prevent restenosis in a cardiovascular lumen.

3. The device of claim 2, wherein the braided body constitutes an electrode.

4. A method for treating cardiovascular disease comprising:

obtaining a radially expandable and collapsible medical device;

placing the medical device, in a radially collapsed state, within a cardiovascular passageway within a body;

positioning the medical device at a target site within the passageway;

placing the medical device in a radially expanded state;

inhibiting restenosis at the target site by a chosen one of electroporation and iontophoresis;

placing the medical device in a radially collapsed state; and

removing the device from the passageway.