Probiotic composition suitable for animals

• US 20100047209A1
• Filed: 04/06/2006
• Published: 02/25/2010
• Est. Priority Date: 04/26/2005
• Status: Active Grant

• Current Assignee: University College Cork (Higher Education Authority), Teagasc - Agricultural & Food Development Authority
• Original Assignee: Teagasc - Agricultural & Food Development Authority
• Inventors: Ross, Paul, Stanton, Catherine, Fitzgerald, Ger, Hill, Colin
• Granted Patent: US 8,603,461 B2
• Time in Patent Office: Days
• US Class Current: 424/93.300
• CPC Class Codes: A23K 10/18 of live microorganisms
• CPC Class Codes: A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 1/14 Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Abstract

The invention provides a probiotic composition to alleviate Salmonella infection in farm animals. The composition may comprise at least one of Lactobacillus murinus, Lactobacillus pentosus, Lactobacillus salivarius sub-species salivarius, and Pediococcus pentosaceus. The composition maybe formulated as an animal feedstuff, or as a pharmaceutical composition.

Claims

1. A probiotic composition comprising one or more microbial cultures selected from the group consisting of Lactobacillus murinus, Lactobacillus pentosus, Lactobacillus salivarius sub-species salivarius, and Pediococcus pentosaceus.

2. A probiotic composition as claimed in claim 1 wherein the cultures are further selected from the group of consisting of Lactobacillus murinus DPC6002, Lactobacillus murinus DPC2003, Lactobacillus pentosus DPC6004, Lactobacillus salivarius sub-species salivarius DPC6005 and Pediococcus pentosaceus DPC6006.

3. A probiotic composition as claimed in claim 1 or claim 2 wherein the cultures are selected from the group consisting of the cultures deposited with the National Collection of Industrial and Marine Bacteria, Aberdeen, Scotland on 25 Apr. 2005 under the Accession Numbers:

NCIMB 41270 Lactobacillus murinus DPC 6002

NCIMB 41271 Lactobacillus murinus DPC 6003

NCIMB 41272 Lactobacillus pentosus DPC 6004

NCIMB 41273 Lactobacillus salivarius DPC 6005

NCIMB 41274 Pediococcus pentosaceous DPC 6006.

4. A probiotic composition comprising all of the strains as claimed in claim 3.

5. A probiotic composition as claimed in any preceding claim wherein the microbial culture is lyophilised or freeze dried.

6. An animal feed composition comprising one or more microbial cultures selected from the group consisting of Lactobacillus murinus, Lactobacillus pentosus, Lactobacillus salivarius sub-species salivarius, and Pediococcus pentosaceus.

7. An animal feed composition as claimed in claim 6 wherein the one or more culture is further selected from the group of consisting of Lactobacillus murinus DPC6002, Lactobacillus murinus DPC2003, Lactobacillus pentosus DPC6004, Lactobacillus salivarius sub-species salivarius DPC6005 and Pediococcus pentosaceus DPC6006.

8. An animal feed composition as claimed in claim 6 or 7 wherein the culture is selected from the group consisting of the cultures deposited with the National Collection of Industrial and Marine Bacteria, Aberdeen, Scotland on 25 Apr. 2005 under the Accession Numbers:

NCIMB 41270 Lactobacillus murinus DPC 6002

NCIMB 41271 Lactobacillus murinus DPC 6003

NCIMB 41272 Lactobacillus pentosus DPC 6004

NCIMB 41273 Lactobacillus salivarius DPC 6005

NCIMB 41274 Pediococcus pentosaceous DPC 6006.

9. A probiotic composition comprising all of the strains as claimed in claim 8.

10. An animal feed composition as claimed in any of claims 6 to 9 wherein the level of the microbial culture is adapted to provide a total dose of at least 3×

0-9 colony forming units per day to the animal being fed

11. A pharmaceutical composition comprising one or more microbial cultures selected from the group consisting of Lactobacillus murinus, Lactobacillus pentosus, Lactobacillus salivarius sub-species salivarius, and Pediococcus pentosaceus.

12. A pharmaceutical composition as claimed in claim 11 wherein the one or more culture is further selected from the group of consisting of Lactobacillus murinus DPC6002, Lactobacillus murinus DPC2003, Lactobacillus pentosus DPC6004, Lactobacillus salivarius sub-species salivarius DPC6005 and Pediococcus pentosaceus DPC6006.

13. A pharmaceutical composition as claimed in claim 11 or 12 wherein the culture is selected from the group consisting of the cultures deposited with the National Collection of Industrial and Marine Bacteria, Aberdeen, Scotland on 25 Apr. 2005 under the Accession Numbers:

NCIMB 41270 Lactobacillus murinus DPC 6002

NCIMB 41271 Lactobacillus murinus DPC 6003

NCIMB 41272 Lactobacillus pentosus DPC 6004

NCIMB 41273 Lactobacillus salivarius DPC 6005

NCIMB 41274 Pediococcus pentosaceous DPC 6006.

14. A pharmaceutical composition comprising all of the strains as claimed in claim 13.

15. A probiotic composition substantially as described herein with reference to the Examples.

16. An animal feed composition substantially as described herein with reference to the Examples.

17. A pharmaceutical composition substantially as described herein with reference to the Examples.