SILVER ANTIMICROBIAL COMPOSITION AND USE

• US 20100047321A1
• Filed: 08/20/2008
• Published: 02/25/2010
• Est. Priority Date: 08/20/2008
• Status: Abandoned Application

• Current Assignee: Eastman Kodak Company
• Original Assignee: Eastman Kodak Company
• Inventors: Bertucci, Sidney J., Mowers, David A., Sandford, David W.
• Application Number:
  US12/194,560
• Publication Number:
  US 20100047321A1
• Time in Patent Office: Days
• US Class Current: 424/443
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16
• CPC Class Codes: A01N 25/22 containing ingredients stabilising the active ingredients
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A61L 15/18 containing inorganic materials
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 2300/104 Silver, e.g. silver sulfadiazine
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/606 Coatings
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: D06M 11/13 Ammonium halides or halides of elements of Groups 1 or 11 of the Periodic Table
• CPC Class Codes: D06M 13/35 Heterocyclic compounds
• CPC Class Codes: D06M 13/352 having five-membered heterocyclic rings
• CPC Class Codes: D06M 13/355 having six-membered heterocyclic rings
• CPC Class Codes: D06M 15/15 Proteins or derivatives thereof
• CPC Class Codes: D06M 16/00 Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
• CPC Class Codes: D06M 23/08 Processes in which the treating agent is applied in powder or granular form adhesives for multi-layer textile fabrics D06M17/00
• CPC Class Codes: D21H 21/36 Biocidal agents, e.g. fungicidal, bactericidal, insecticidal agents

Abstract

Aqueous silver-containing composition is designed for use as an antimicrobial agent on fibers and fabrics. This composition includes silver halide particles, gelatin, and an additive that includes an N-heterocyclic acid having a pKa of from about 4 to about 9. The additive improves the redispersibility and shelf-life of the composition.

Claims

1. A composition comprising at least 50 weight % water, silver halide particles, gelatin, and an additive that includes one or more N-heterocyclic acids at least one of which has a pKa of from about 4 to about 9, wherein said composition is substantially free of organic solvents.

2. The composition of claim 1 wherein said N-heterocyclic acid is an azole.

3. The composition of claim 1 wherein said N-heterocyclic acid is a triazole.

4. The composition of claim 1 wherein said N-heterocyclic acid is a diazole.

5. The composition of claim 1 wherein said N-heterocyclic acid has a pKa of from about 4.5 to about 8.5.

6. The composition of claim 1 wherein said N-heterocyclic acid is one or more of the following compounds:

tetraazaindene, bromo-tetraazaindene, S-methyl-tetraazaindene, urazole, uric acid, benzotriazole, methylbenzotriazole, and chloronitrobenzotriazole.

7. The composition of claim 1 wherein said additive is present in an amount of from about 0.1 to about 5 weight % relative to the amount of silver.

8. The composition of claim 1 wherein gelatin is present in an amount of less than 1.3 weight %.

9. The composition of claim 1 wherein said silver halide particles are predominantly silver chloride.

10. The composition of claim 1 wherein said silver halide particles are present in an amount of from about 1×

10<sup>−

7</sup> to about 20% by weight.

11. The composition of claim 1 wherein said silver halide particles are present in an amount of from about 1×

10<sup>−

4</sup> to about 10% by weight.

12. The composition of claim 1 wherein said silver halide particles are predominantly less than 1 μ

m in diameter.

13. The composition of claim 1 that does not substantially gel or solidify at 25°

C.

14. The composition of claim 1 comprising at least 90 weight % water, silver chloride particles in an amount of from about 0.001 to about 4 weight %, gelatin in an amount of from about 0.15 to about 1 weight %, and an additive that includes one or both of uric acid and methylbenzotriazole in an amount of from about 0.5 to about 2 weight % relative to the amount of silver, wherein said composition is substantially free of organic solvents.

20. A method of providing an antimicrobial coating comprising:

coating a fiber, fabric, or substrate with the composition of claim 1, and

drying the coated fiber, fabric, or substrate.

21. A fiber, fabric, or substrate having a dried antimicrobial coating provided from the composition of claim 1.

15. A composition consisting essentially of water, silver halide particles, gelatin, and an additive that includes one or more N-heterocyclic acids at least one of which has a pKa of from about 4 to about 9.

16. The composition of claim 15 wherein said N-heterocyclic acid is an azole.

17. The composition of claim 15 wherein said N-heterocyclic acid is one or more of the following compounds:

tetraazaindene, bromo-tetraazaindene, S-methyl-tetraazaindene, urazole, uric acid, benzotriazole, methylbenzotriazole, and chloronitrobenzotriazole.

18. The composition of claim 15 wherein gelatin is present in an amount of less than 1 weight %.

19. The composition of claim 15 wherein said silver halide particles are predominantly silver chloride and are present in an amount of from about 1×

10<sup>−

7</sup> to about 10% by weight.