DEVICES AND METHODS FOR ACCELEROMETER-BASED CHARACTERIZATION OF CARDIAC FUNCTION AND IDENTIFICATION OF LV TARGET PACING ZONES
First Claim
1. A device for monitoring cardiac function, comprising:
- a. At least one acceleration sensor for disposition within or on a patient'"'"'s heart;
b. Wherein the acceleration sensor includes means for sensing both vibrational and displacement motion frequencies.
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Accused Products
Abstract
Systems according to the invention employ an acceleration sensor to characterize displacement and vibrational LV motion, and uses this motion data to characterize the different phases of the LV cycle for analyzing LV function. Systems may identify a target pacing region or regions in the LV or RV using the acceleration sensor by localizing regions of late onset of motion relative to the QRS, or isovolumic contraction, or mitral valve closure, or by pacing of target regions and measuring LV function in response to pacing. Systems further provide an implantable or non-implantable acceleration sensor device for measuring LV motion and characterizing LV function. An implantable myocardial acceleration sensing system (“IAD”) includes at least one acceleration sensor, a data acquisition and processing device, and an electromagnetic, e.g., RF, communication device. The IAD may be integrated into the pacing lead of a CRT device and can operate independently of the CRT IPG.
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Citations
35 Claims
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1. A device for monitoring cardiac function, comprising:
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a. At least one acceleration sensor for disposition within or on a patient'"'"'s heart; b. Wherein the acceleration sensor includes means for sensing both vibrational and displacement motion frequencies. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 28, 29)
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20. A method for identifying CRT pacing regions, comprising:
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a. Placing an acceleration sensing device in a patient'"'"'s heart; b. Sensing acceleration signals at one or more frequencies; c. Comparing the sensed acceleration signals to a reference point indicative of the start of systole or diastole.
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21. A method for monitoring cardiac function, comprising:
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a. Placing at least two acceleration sensing devices in a patient'"'"'s heart; b. Sensing acceleration signals at two or more frequencies. - View Dependent Claims (22)
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23. A method for monitoring cardiac function, comprising:
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a. Placing at least two acceleration sensing devices in a patient'"'"'s heart; b. Sensing acceleration signals at one or more frequencies; c. Wherein one of the devices measures vibrational motion and another measures displacement motion. - View Dependent Claims (24)
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25. A method for identifying CRT pacing regions, comprising:
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a. Placing a sensing device in a patient'"'"'s heart; b. Pacing target pacing regions with a pacing device; c. Measuring signals corresponding to heart function; d. Placing a CRT lead is a region where the pacing causes a favorable change in the heart function signal. - View Dependent Claims (26)
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27. A method for identifying CRT pacing regions, comprising:
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a. Placing an acceleration sensing device in a patient'"'"'s heart; b. Pacing target pacing regions with a pacing device; c. In response to the pacing, measuring acceleration signals indicative of LV function.
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30. A method for identifying CRT pacing regions, comprising:
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a. Placing an acceleration sensing device in a patient'"'"'s heart; b. Sensing acceleration signals at one or more frequencies; c. Identifying regions of late onset of motion from the sensed acceleration signals; d. Wherein said regions of late onset of motion are the CRT pacing regions. - View Dependent Claims (31)
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32. A method for identifying cardiac features, comprising:
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a. Placing an acceleration sensing device in a patient'"'"'s heart, the device including a catheter with an acceleration sensor disposed at or near the distal tip of the catheter; b. Moving said device in proximity to a cardiac feature; c. Sensing signals corresponding to vibration or deflection due to blood flow from the cardiac feature. - View Dependent Claims (33, 34)
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35. A device for monitoring acceleration of tissue in a human body, comprising:
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a. At least one acceleration sensor chip for disposition within or on a tissue in a patient; b. A flexible circuit mounted to said sensor chip for carrying signals from said sensor chip to a signal analysis unit; c. At least one capacitor disposed on the flexible circuit adjacent said sensor chip for decoupling or attenuating noise voltages such that the signal to noise ratio of signals from said sensor chip to reach the signal analysis unit is higher than in the absence of said at least one capacitor.
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Specification