MEDICAMENT DELIVERY DEVICE, CAPSULE AND IN VIVO MEDICINE DELIVERY OR DIAGNOSTIC SYSTEM

• US 20100056874A1
• Filed: 11/06/2007
• Published: 03/04/2010
• Est. Priority Date: 11/21/2006
• Status: Active Grant

• Current Assignee: Biora Therapeutics Incorporated
• Original Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Inventors: De Jongh, Frits Tobi, Iordanov, Ventzeslav, Boeve, Hans Marc Bert, Shimizu, Jeff, Dijksman, Johan Frederik, Pierik, Anke, Pardoel, Michel Gerardus, Rensen, Judith Margreet, Zou, Hans, Albu, Remus
• Granted Patent: US 9,878,094 B2
• Time in Patent Office: Days
• US Class Current: 600/300
• CPC Class Codes: A61B 1/041 Capsule endoscopes for imaging
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/073 Intestinal transmitters
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2005/14204 with gas-producing electrochemical cell
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure

Abstract

A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.

Claims

1. Medicament delivery device, comprising a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21), and a driving mechanism, which is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25).

2. Medicament delivery device according to claim 1, wherein the housing (1) comprises a first part (11) and a second part (12), in which the first part (11) of the housing (1) is secured to the second part (12) of the housing (1) thereby clamping the flexible wall (21) in between the first part (11) of the housing (1) and the second part (12) of the housing (1) and separating the drive mechanism from the reservoir (2).

3. Medicament delivery device according to claim 2, wherein the first part (11) of the housing (1) comprises a protrusion (31) and the second part (12) of the housing comprises a recess (32), in which the flexible wall (21) is clamped in between the first part (11) of the housing (1) and the second part (12) of the housing (1) by insertion of the protrusion (31) into the recess (32) thereby securing the first part (11) of the housing (1) to the second part (12) of the housing (1).

4. Medicament delivery device according to claim 1, wherein the piston (23) is provided with a threaded hole and is driven by a threaded component (24) of the drive mechanism, which threaded component (24) is mounted onto an electrical motor (22).

5. Medicament delivery device according to claim 1, wherein a part of a surface (26) of the piston (23) that contacts the flexible wall (21) during release of the substance from the reservoir (2) comprises a low friction material.

6. Capsule for introduction into a bodily lumen comprising a medicament delivery device according to claim 1 and electronic circuitry (40) to control the piston (23).

7. In vivo medicament delivery or diagnostic system comprising a capsule according to claim 6 and an external device arranged to communicate with the electronic circuitry (40).